5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

Names

[ Name ]:
5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

[Synonym ]:
10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin Dihydrochloride Salt
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-, (4S)-
(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
>168° C (dec.)

[ Melting Point ]:
>168° C (dec.)

[ Molecular Formula ]:
C₂₃H₂₃N₃O₆・₂HCl

[ Molecular Weight ]:
510.37

[ Flash Point ]:
467.4±34.3 °C

[ Exact Mass ]:
437.158691

[ LogP ]:
-0.09

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.754

[ Water Solubility ]:
Soluble in DMSO, methanol, and water.

Related Compounds

2-[5-methyl-4-(2-methylpropyl)-4H-1,2,4-triazol-3-yl]piperidine
(7-Methylquinolin-8-yl)methanol
1-(3-Methyl-5-(piperidin-2-yl)-4H-1,2,4-triazol-4-yl)propan-2-ol
tert-butyl N-(2,5-dimethylpiperidin-4-yl)-N-methylcarbamate
1-(2-chloro-4-methylphenyl)-1H-pyrazole-5-sulfonamide
1-(2-chloro-6-methylphenyl)-1H-pyrazole-5-sulfonamide
2-[5-methyl-4-(3-methylbutyl)-4H-1,2,4-triazol-3-yl]morpholine
3-Methoxy-3-[(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methyl]azetidine
1-(2-chloro-4-methylphenyl)-N-methyl-1H-pyrazole-5-sulfonamide
6-[(2-Methyl-1,3-benzothiazol-5-yl)amino]pyridazine-3-carbonitrile

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