5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

Names

[ CAS No. ]:
504413-73-4

[ Name ]:
5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

[Synonym ]:
10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin Dihydrochloride Salt
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-, (4S)-
(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
>168° C (dec.)

[ Melting Point ]:
>168° C (dec.)

[ Molecular Formula ]:
C23H23N3O6・2HCl

[ Molecular Weight ]:
510.37

[ Flash Point ]:
467.4±34.3 °C

[ Exact Mass ]:
437.158691

[ LogP ]:
-0.09

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.754

[ Water Solubility ]:
Soluble in DMSO, methanol, and water.

Related Compounds

  • 4-((1-(2-((2,4-dimethylphenyl)amino)-2-oxoethyl)-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(3-methoxypropyl)benzamide
  • 2-((2-Ethylhexyl)amino)-4-oxo-4-(pyridin-3-ylamino)butanoic acid
  • [4-(Ethoxymethoxy)phenyl]methanol
  • Ethyl 2-(aminomethyl)oxazole-5-carboxylate
  • Ethyl 2-(aminomethyl)-4-methyloxazole-5-carboxylate
  • 1-Methoxy-2-(4-phenyl-1-butoxy)-4-bromobenzene
  • Ethyl 4-(4-chlorophenyl)-5-(2,4-dichlorophenyl)-1,3-thiazole-2-carboxylate
  • 4-[[5-(Aminocarbonyl)-2-naphthalenyl]oxy]-7-methoxy-6-quinolinecarboxamide
  • 2-Chloro-5-(2,4-dichlorophenyl)pyridine
  • Alanylphenylalanine methyl ester
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