Iberin

Suppliers

Names

[ CAS No. ]:
505-44-2

[ Name ]:
Iberin

[Synonym ]:
sulfpraphane
3-isothiocyanatopropyl methyl sulfoxide
METHYLSULFINYLPROPYLISOTHIOCYANATE
Propane, 1-isothiocyanato-3-(methylsulfinyl)-
3-Methylsulfinylpropyl isothiocyanate
Iberin
1-Isothiocyanato-3-(methylsulfinyl)propane
C5H9NOS2
3-Methylsulphinylpropylisothiocyanate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
362.4±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H9NOS2

[ Molecular Weight ]:
163.261

[ Flash Point ]:
173.0±23.2 °C

[ Exact Mass ]:
163.012558

[ PSA ]:
80.73000

[ LogP ]:
-0.05

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.577

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX8950000
CHEMICAL NAME :
Isothiocyanic acid, 3-(methylsulfinyl)propyl ester
CAS REGISTRY NUMBER :
505-44-2
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H9-N-O-S2
MOLECULAR WEIGHT :
163.27
WISWESSER LINE NOTATION :
SCN3SO&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Behavioral - coma
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,159,1980 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
100 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,159,1980

Synthetic Route

Precursor & DownStream

Precursor

  • Thiophosgene
  • 3-Methanesulfinylpropan-1-amine
  • Carbon disulphide

DownStream


Related Compounds

  • Iberin nitrile
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-(4-Methylbenzenesulfonyl)propan-2-amine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide