Fenspiride

Suppliers

Names

[ CAS No. ]:
5053-06-5

[ Name ]:
Fenspiride

[Synonym ]:
8-phenethyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-
Fluiden
Fenspiridum [INN-Latin]
Fenspiride [INN]
EINECS 225-751-3
Viarespan
1-Oxa-3,8-diazaspiro[4.5]dec-2-en-2-ol, 8-(2-phenylethyl)-
8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Fenspiride
Respiride
Fenspirida [INN-Spanish]

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
408.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H20N2O2

[ Molecular Weight ]:
260.332

[ Flash Point ]:
200.7±31.5 °C

[ Exact Mass ]:
260.152466

[ PSA ]:
41.57000

[ LogP ]:
1.91

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.609

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RO0373000
CHEMICAL NAME :
1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-phenethyl-
CAS REGISTRY NUMBER :
5053-06-5
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H20-N2-O2
MOLECULAR WEIGHT :
260.37
WISWESSER LINE NOTATION :
T6N CXTJ A2R& C-& DT5MVOX EHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 4,185,1969

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Triphosgene
  • 4-(aminomethyl)-1-(2-phenylethyl)piperidin-4-ol
  • 1-Phenethyl-4-piperidone
  • Ethyl carbonate

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Fenspiride HCl
  • Fenspiride N-Oxide
  • 4-Hydroxy Fenspiride
  • 3-Hydroxy Fenspiride
  • 2-Hydroxy Fenspiride
  • Fenspiride-d5 hydrochloride
  • 2-Methoxyethyl 3-amino-4-(6-methoxyquinolin-2-yl)benzoate
  • Ethyl 4-[6-methoxy-3-(trifluoromethyl)-2-quinolinyl]cyclohexanecarboxylate
  • Methyl 4-(6-hydroxyquinolin-2-yl)cyclohex-3-enecarboxylate
  • 2-((Tert-butyldimethylsilyloxy)methyl)-4-methoxyaniline
  • 3-Chloro-4-(6-hydroxyquinolin-2-yl)benzamide
  • 1-(4-fluoro-2-methylphenyl)-3-methyl-1H-1,2,4-triazol-5-amine
  • 4-(6-Hydroxyquinolin-2-yl)benzonitrile
  • Methyl 4-(6-methoxyquinolin-2-yl)benzoate
  • Methyl 4-(5-bromo-6-methoxyquinolin-2-yl)benzoate
  • Methyl 1-(6-methoxy-3-(trifluoromethyl)quinolin-2-yl)piperidine-4-carboxylate
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