4-Amino-1-benzylpiperidine

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Names

[ CAS No. ]:
50541-93-0

[ Name ]:
4-Amino-1-benzylpiperidine

[Synonym ]:
4-Piperidin-1-ylmethyl-phenylamine
4-amino-benzylpiperidine
MFCD03422516
N-Benzyl-4-amino piperidine
4-(Piperidin-1-ylmethyl)benzenamine
4-Piperidinamine, 1-(phenylmethyl)-
1-benzyl-4-aMino
EINECS 256-620-9
4-Amino-1-Benzylpiperidine
1-Benzylpiperidin-4-amin
N-Benzyl-4-piperidinamine
4-(Piperidin-1-ylmethyl)aniline
1-Benzyl-4-piperidinamine
1-Benzylpiperidin-4-amine
1-(Phenylmethyl)-4-piperidinamine
1-Benzyl-4-aminopiperidine
1-Benzyl -4-amino piperidine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
281.2±33.0 °C at 760 mmHg

[ Melting Point ]:
90-93ºC

[ Molecular Formula ]:
C12H18N2

[ Molecular Weight ]:
190.285

[ Flash Point ]:
113.9±20.5 °C

[ Exact Mass ]:
190.147003

[ PSA ]:
29.26000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.561

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
immiscible

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29333999

Synthetic Route

Precursor & DownStream

Precursor

  • 1-Benzylpiperidin-4-one oxime
  • 1-Benzylpiperidone
  • Ethanol
  • 1-Benzylpiperidine-4-carboxyamide
  • 1-Benzyl-4-(N-Boc-amino)piperidine
  • N-Benzyl-4-piperidone
  • Benzyl bromide
  • 2-[1-(Phenylmethyl)-4-piperidinyl]-1H-isoindol-1,3(2H)-dione
  • 1-BENZYL-PIPERIDINE-4-CARBOXYLIC ACID HYDRAZIDE
  • Benzyl chloride

DownStream

  • n-piperidin-4-yl-benzamide
  • 4-Acetamido-1-benzylpiperidine
  • 1-(4-Piperidinyl)-2-pyrrolidinone
  • N-(1-benzylpiperidin-4-yl)-2-bromoacetamide(SALTDATA: 0.35HCl)
  • N-(1-benzylpiperidin-4-yl)-2-(2-bromophenyl)acetamide
  • N-(1-Benzylpiperidin-4-yl)-3-nitropyridin-2-amine
  • N-(1-benzylpiperidin-4-yl)-2-(2-nitrophenyl)acetamide
  • 4-(TERT-BUTOXYCARBONYLAMINO)-1-[(6-AMINOPYRIDIN-2-YL)METHYL]PIPERIDINE
  • 4-(TERT-BUTOXYCARBONYLAMINO)-1-[(6-BROMOPYRIDIN-2-YL)METHYL]PIPERIDINE
  • 4-Amino-1-Boc-piperidine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Studies on the collision-induced dissociation of adipoR agonists after electrospray ionization and their implementation in sports drug testing.

J. Mass Spectrom. 50(2) , 407-17, (2015)

AdipoR agonists are small, orally active molecules capable of mimicking the protein adiponectin, which represents an adipokine with antidiabetic and antiatherogenic effects. Two adiponectin receptors ...

N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors.

Eur. J. Med. Chem. 35(10) , 913-22, (2000)

A new family of 1,2,4-thiadiazolidinone derivatives containing the N-benzylpiperidine fragment has been synthesised. The acetylcholinesterase (AChE) inhibitory activity of all compounds was measured u...

Synthesis of new glycyrrhetinic acid (GA) derivatives and their effects on tyrosinase activity.

Bioorg. Med. Chem. 11(24) , 5345-52, (2003)

To synthesize glycyrrhetinic acid (GA) derivatives (3, 4, 5, 10, 13, 14, 15, and 16), we first removed the ketonic group in the C-11 position, and the carboxylic function at the C-30 position was kept...


More Articles


Related Compounds

  • 4-AMINO-1-BENZYLPIPERIDINE 2HCLHYDRATE
  • 4-Amino-1-benzylpiperidine-4-carboxamide
  • 4-Amino-1-benzylpiperidine-4-carbonitrile
  • 4-Amino-1-benzylpiperidine-4-carboxylic Acid
  • Methyl4-Amino-1-benzylpiperidine-4-carboxylate
  • ethyl 4-amino-1-benzylpiperidine-3-carboxylate