2-Bromo-2-methylpropane

Suppliers

Names

[ CAS No. ]:
507-19-7

[ Name ]:
2-Bromo-2-methylpropane

[Synonym ]:
t-Butyl bromide
EINECS 208-065-9
t-butylbromide
2-Bromo-2-methylpropane
Tertiary butyl bromide
Propane,2-bromo-2-methyl
1-bromo-1,1-dimethylethane
2-methyl-2-bromopropane
Bromotrimethylmethane
2-Bromo-2-methyl-propane
Tertiarybutyl bromide
Trimethylbromomethane
Propane, 2-bromo-2-methyl-
2-Bromoisobutane
MFCD00000125
tert-butyl bromide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
73.2±0.0 °C at 760 mmHg

[ Melting Point ]:
-20 °C

[ Molecular Formula ]:
C4H9Br

[ Molecular Weight ]:
137.018

[ Flash Point ]:
18.3±0.0 °C

[ Exact Mass ]:
135.988754

[ LogP ]:
2.38

[ Vapour Pressure ]:
125.7±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.438

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX4150000
CHEMICAL NAME :
Propane, 2-bromo-2-methyl-
CAS REGISTRY NUMBER :
507-19-7
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-Br
MOLECULAR WEIGHT :
137.04
WISWESSER LINE NOTATION :
EX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,29,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,29,1982 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3000 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1411,1975

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;Xi:Irritant;

[ Risk Phrases ]:
R11;R36/37/38

[ Safety Phrases ]:
S16-S33-S37/39-S26

[ RIDADR ]:
UN 2342 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TX4150000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29033036

Synthetic Route

Precursor & DownStream

Precursor

  • tert-Butanol
  • 2-Chlorobutane
  • tert-butyl chloride
  • Isobutane Residual Solvent Standard
  • Propane,2-iodo-2-methyl-
  • Isobutylene
  • 1-Chlorobutane
  • Methyl tert-butyl ether
  • carbon monoxide
  • Benzyl bromide

DownStream

  • 6-tert-butylnaphthalen-2-ol
  • 2,2-DIMETHYLHEPTANE
  • Decane
  • ethyl 2-[(2-methylpropan-2-yl)oxyimino]-3-oxobutanoate
  • (E)-1-chloro-3-(1-propenyl)-benzene
  • 1-chloro-3-(4,4-dimethylpent-1-en-3-yl)benzene
  • (E)-1-chloro-3-(4,4-dimethylpent-1-en-1-yl)benzene
  • 1-tert-Butyl-4-chlorobenzene
  • Methyl isovalerate
  • Methyl pivalate

Customs

[ HS Code ]: 29033036

Articles

Deguanylation of guanine based-nucleosides and calf thymus DNA induced by halogenated alkanes at the physiological condition. Sherchan J and Lee E-S.

Bull. Korean Chem. Soc. 30(12) , 2318-2328, (2009)

Deadenylation of Adenine Based-Nucleosides and Calf thymus DNA Induced by Halogenated Alkanes at the Physiological Condition. Sherchan J, et al.

Bull. Korean Chem. Soc. 30(10) , 2318-2328, (2009)


More Articles


Related Compounds

  • 2-Bromo-2-methylpropane-d9
  • 2-bromo-2-methylpropane-1-thiol
  • dimethyl 2-bromo-2-methylpropanedioate
  • 2-bromo-1-chloro-2-methylpropane
  • 2-bromo-1,1,1-trifluoro-2-methylpropane
  • 2-bromo-2-chloro-1-(4-methylphenyl)ethanone