1-(Hydroxymethyl)-1H-indole-2,3-dione

Names

[ CAS No. ]:
50899-59-7

[ Name ]:
1-(Hydroxymethyl)-1H-indole-2,3-dione

[Synonym ]:
1-(hydroxymethyl)indole-2,3-dione
1-(HYDROXYMETHYL)ISATIN

Chemical & Physical Properties

[ Density]:
1.462g/cm3

[ Boiling Point ]:
364.3ºC at 760mmHg

[ Molecular Formula ]:
C9H7NO3

[ Molecular Weight ]:
177.15700

[ Flash Point ]:
174.1ºC

[ Exact Mass ]:
177.04300

[ PSA ]:
57.61000

[ LogP ]:
0.23070

[ Index of Refraction ]:
1.644

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL7931000
CHEMICAL NAME :
Indole-2,3-dione, 1-(hydroxymethyl)-
CAS REGISTRY NUMBER :
50899-59-7
BEILSTEIN REFERENCE NO. :
0153590
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H7-N-O3
MOLECULAR WEIGHT :
177.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
785 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - antipsychotic
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 37,858,1982

Synthetic Route

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Precursor & DownStream

Precursor

  • Formaldehyde
  • isatin

DownStream

Related Compounds

  • 5-Ethyl-1-(hydroxymethyl)-1H-indole-2,3-dione
  • 5-chloro-1-(hydroxymethyl)indole-2,3-dione
  • 5-chloro-1H-indole-2,3-dione 3-oxime
  • 1-Propionyl-1H-indole-2,3-dione
  • 1-ISOPROPYL-1H-INDOLE-2,3-DIONE
  • 1-(Dimethylamino)-1H-indole-2,3-dione