Gelsemine

Suppliers

Names

[ CAS No. ]:
509-15-9

[ Name ]:
Gelsemine

[Synonym ]:
GELSAMINE
8abeta,9s*,10s*))-8alph
GESEMINE
(2'S,3S,5'S,6'R,8'R,11'S)-4'-Methyl-2'-vinylspiro[indole-3,7'-[9]oxa[4]azatetracyclo[6.3.1.0.0]dodecan]-2(1H)-one
gelsemine free base
Gelsemin
EINECS 208-095-2

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
493.4±45.0 °C at 760 mmHg

[ Melting Point ]:
181-183ºC

[ Molecular Formula ]:
C20H22N2O2

[ Molecular Weight ]:
322.401

[ Flash Point ]:
252.2±28.7 °C

[ Exact Mass ]:
322.168121

[ PSA ]:
41.57000

[ LogP ]:
3.08

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.673

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LX9100000
CHEMICAL NAME :
Gelsemine
CAS REGISTRY NUMBER :
509-15-9
BEILSTEIN REFERENCE NO. :
5406576
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H22-N2-O2
MOLECULAR WEIGHT :
322.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,349,1957

Safety Information

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
23/24/25-26/27/28

[ Safety Phrases ]:
36/37/39-45-28

[ RIDADR ]:
UN 1544 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
LX9100000

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(a)

Precursor & DownStream

Precursor

  • 21-oxogelsemine

DownStream

Related Compounds

  • Gelsemine HCl
  • 1-methoxy-18,19-dihydro-gelsemine
  • 2-Iodo-5-(4-methylphenyl)furan
  • Acetic acid, chloro(phenylazo)-
  • rac-[(1R,3R)-3-(2,3-dihydro-1,4-benzodioxin-5-yl)-2,2-dimethylcyclopropyl]methanamine
  • 5-(2-chlorobenzyl)-2-(4-fluorophenyl)-3-(hydroxymethyl)pyrazolo[1,5-a]pyrazin-4(5H)-one
  • (I+/-S)-I+/--Heptylbenzenemethanamine
  • 6-(Pyrimidin-4-yloxy)-2-azaspiro[3.3]heptane
  • (R)-6-Chloro-5-fluoro-2,3-dihydro-1H-inden-1-amine
  • tert-Butyl 2-(benzyloxy)-1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate
  • 2-(Difluoromethoxy)-6-hydroxybenzoic acid
  • 2-Deoxy-2,2-difluoro-3,5-dibenzoate D-erythro-Pentitol
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.