Strychnine, 2-methoxy

Names

[ CAS No. ]:
509-36-4

[ Name ]:
Strychnine, 2-methoxy

[Synonym ]:
2-methoxy-sym-triazine
2-methoxy-s-triazine
2-Methoxy-symm.-triazin
2-methoxy-strychnidin-10-one
2-Methoxy-strychnidin-10-on
2-Methoxy-1,3,5-triazin
2-Methoxy-strychnin

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
609.6ºC at 760 mmHg

[ Molecular Formula ]:
C22H24N2O3

[ Molecular Weight ]:
364.43800

[ Flash Point ]:
322.5ºC

[ Exact Mass ]:
364.17900

[ PSA ]:
42.01000

[ LogP ]:
2.10400

[ Index of Refraction ]:
1.703

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GJ9990000
CHEMICAL NAME :
beta-Colubrine
CAS REGISTRY NUMBER :
509-36-4
LAST UPDATED :
199206
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H24-N2-O3
MOLECULAR WEIGHT :
364.48
WISWESSER LINE NOTATION :
T6 G656 B7 C5 E5 D 5ABCEF A& FX MNV QO VN AH SUT&&TTTTJ IO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8700 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 7,329,1970

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • diazomethane
  • 7,9-Methano-7H-oxepino[3,4-a]pyrrolo[2,3-d]- carbazole-13-acetic acid,5,6,7a,8,8a,11,13,13a,13b,14-decahydro-,(4bS,7S,7aS,8aR,13S,13aR,13bS)-
  • 2-aminostrychnin

DownStream

Related Compounds

  • 1-(2-methoxy-5-methylphenyl)-2-pyridin-2-ylethanone
  • methyl 2-methoxy-5-pivaloyloxybenzoate
  • 3-(2-METHOXY-PHENYL)-PROPIONYL CHLORIDE
  • 3-(2-methoxy-5-nitro-pyridin-4-yl)-2-oxo-propionic acid ethyl ester
  • (Hydroxy-2-methoxy-3-phenyl)-2-hydroxy-2-indandione-1,3
  • 1-(2-METHOXY-6-((4-METHOXYBENZYL)OXY)PHENYL)ETHANONE
  • 2,2-dimethyl-N-{[1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl]methyl}propanamide
  • N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)furan-2-carboxamide
  • N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamide
  • N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-3-carboxamide
  • (E)-3-(furan-2-yl)-N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)acrylamide
  • 7-Chloro-2-(thiophen-3-yl)imidazo[1,2-a]pyridine
  • 8-Chloro-2-(thiophen-3-yl)imidazo[1,2-a]pyridine
  • 2,5-dimethyl-N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)furan-3-carboxamide
  • 2-(thiophen-2-yl)-N-((1-(thiophen-3-yl)-1H-1,2,3-triazol-4-yl)methyl)acetamide
  • 1-ethyl-3-methyl-N-[(1-propyl-1H-pyrazol-4-yl)methyl]-1H-pyrazol-5-amine
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