α-Colubrine

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Names

[ CAS No. ]:
509-44-4

[ Name ]:
α-Colubrine

[Synonym ]:
3-methoxy-strychnine
3-Methoxy-strychnin
3-Methoxystrychnidin-10-one
Strychnidin-10-one,3-methoxy
3-Methoxy-strychnidin-10-on

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
599.4ºC at 760 mmHg

[ Molecular Formula ]:
C22H24N2O3

[ Molecular Weight ]:
364.43800

[ Flash Point ]:
316.3ºC

[ Exact Mass ]:
364.17900

[ PSA ]:
42.01000

[ LogP ]:
2.10400

[ Index of Refraction ]:
1.703

Synthetic Route

Precursor & DownStream

Precursor

  • (4aR,5aS,13aS,15aS,15bR)-11-nitro-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one
  • 2-amino-3-nitro-strychnidin-10-one, sulfate (2:1)
  • diazomethane
  • 11-hydroxystrychnine
  • Malonic acid
  • (17R,19E)-17,18-epoxy-11-methoxy-cur-19-en-17-ol

DownStream


Related Compounds

  • 18-oxo-α-colubrine
  • α-(3,4-Dimethoxyphenyl)-4-[(3,4-dimethoxyphenyl)methyl]tetrahydro-3-hydroxyfuran-3-methanol
  • α-((N-(2-aminobenzyl)-N-methylamino)methyl)-3,4-dimethoxybenzyl alcohol
  • α-(((2-nitrobenzylidene)amino)methyl)-3,4-dimethoxybenzyl alcohol
  • α,3-Bis(acetyloxy)-5-methoxybenzeneacetic acid methyl ester
  • α-(1-Hydroxyethyl)benzenessigsaeure-methylester
  • (3R)-3-{[(benzyloxy)carbonyl]amino}-3-[3-(benzyloxy)phenyl]propanoic acid
  • 2-({1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-iodophenyl]-N-methylformamido}oxy)acetic acid
  • 4-(1,5-dimethyl-1H-pyrazol-3-yl)butan-1-amine
  • 3-[3-Chloro-4-(trifluoromethyl)phenyl]butanoic acid
  • 1-ethyl-3-(2-methylbut-3-yn-2-yl)-1H-pyrazole
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(1,2,4-triazin-3-yl)carbamoyl]propanoic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,2-dimethylpropanamido]benzoic acid
  • 1-[1-(2-Chloro-6-methylphenyl)cyclopropyl]ethan-1-ol
  • rac-(1R,3S)-2,2-dimethyl-3-(4,5,6,7-tetrahydro-1H-indol-2-yl)cyclopropan-1-amine
  • (2R)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-dimethylpropanamido]-4-hydroxybutanoic acid
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