7-Diethylaminocoumarin-3-carboxylic acid

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Names

[ CAS No. ]:
50995-74-9

[ Name ]:
7-Diethylaminocoumarin-3-carboxylic acid

[Synonym ]:
7-diethylaminocoumarin-3-carboxylic acid
7-(Diethylamino)coumarin-3-carboxylic Acid
2H-1-Benzopyran-3-carboxylic acid, 7-(diethylamino)-2-oxo-
7-(Diethylamino)-2-oxo-2H-chromene-3-carboxylic acid
7-(diethylamino)-2-oxochromene-3-carboxylic acid
7ACC1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
464.7±45.0 °C at 760 mmHg

[ Melting Point ]:
222-224ºC (dec.)(lit.)

[ Molecular Formula ]:
C14H15NO4

[ Molecular Weight ]:
261.273

[ Flash Point ]:
234.9±28.7 °C

[ Exact Mass ]:
261.100098

[ PSA ]:
70.75000

[ LogP ]:
3.34

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.618

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932209090

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl 7-(Diethylamino)coumarin-3-carboxylate
  • Meldrumic acid
  • 4-Diethylaminosalicylaldehyde
  • Diethyl malonate
  • methyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate
  • 4-DIETHYLAMINOSALICYLIC ACID
  • 2-cyano-3-(4-diethylamino-2-acetoxyphenyl)acrylonitrile
  • 3-CYANO-7-(DIETHYLAMINO)COUMARIN
  • 7-diethylamino-2-imino-2H-chromene-3-carbonitrile

DownStream

  • Coumarin 466
  • 7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester
  • 7-DIETHYLAMINO-3-PHENYLCOUMARIN
  • 7-(Diethylamino)-2-oxochromene-3-carbaldehyde

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Photophysical properties of 7-(diethylamino)coumarin-3-carboxylic acid in the nanocage of cyclodextrins and in different solvents and solvent mixtures.

Photochem. Photobiol. , (2012)

The photophysical properties of 7-(diethylamino) coumarin-3-carboxylic acid (7-DCCA) were studied in cyclodextrins (α, β, γ,-CDs), different neat solvents and solvent mixtures by using steady state ab...

Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid.

J. Biol. Chem. 276(27) , 24985-90, (2001)

GM1 ganglioside-bound amyloid beta-protein (GM1/Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) including diffuse plaques, has been suggested to be involved i...

Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid.

Biochemistry 41(23) , 7385-90, (2002)

GM1 ganglioside-bound amyloid beta-protein (GM1-Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) plaques, has been suggested to accelerate amyloid fibril forma...


More Articles


Related Compounds

  • 7-diethylaminocoumarin-3-carboxylic acid
  • 7-diethylaminocoumarin-3-carboxylic acid
  • 7-diethylaminocoumarin-3-carboxylic acid ethyl ester
  • Hexyl 7-(Diethylamino)coumarin-3-carboxylate
  • 7-Methoxyquinoline-3-carboxylic acid hydrochloride
  • 7-aminoquinoline-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-Isocyanato-1-(1,2,2,2-tetrafluoroethyl)cyclopropane
  • 4-Amino-3-(2-methyl-6-nitrophenyl)butanoic acid
  • 4-[2-Fluoro-4-(trifluoromethyl)phenyl]-2-methylbutan-2-amine
  • tert-butyl N-[2-(1-amino-3,3-difluorocyclobutyl)-4-fluorophenyl]carbamate
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide