Urea,N-(aminoiminomethyl)-N'-(4-nitrophenyl)-, hydrochloride (1:1)

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Names

[ CAS No. ]:
51-58-1

[ Name ]:
Urea,N-(aminoiminomethyl)-N'-(4-nitrophenyl)-, hydrochloride (1:1)

[Synonym ]:
N-carbamimidoyl-N'-(4-nitro-phenyl)-urea,hydrochloride
Nitroguanil
N-Carbamimidoyl-N'-(4-nitro-phenyl)-harnstoff,Hydrochlorid

Chemical & Physical Properties

[ Boiling Point ]:
421.2ºC at 760mmHg

[ Molecular Formula ]:
C₈H₉ClN₅O₃-

[ Molecular Weight ]:
258.64200

[ Flash Point ]:
208.5ºC

[ Exact Mass ]:
258.03900

[ PSA ]:
136.82000

[ Index of Refraction ]:
1.695

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YR8166000

CHEMICAL NAME :: Urea, 1-amidino-3-(p-nitrophenyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 51-58-1

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H9-N5-O3.Cl-H

MOLECULAR WEIGHT :: 259.68

WISWESSER LINE NOTATION :: WNR DMVMYZUM &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 38,425,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,521,1967 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 35 mg/kg

SEX/DURATION :: female 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 13,228,1968

Precursor & DownStream

Precursor

DownStream

1-ethyl-3-(4-nitrophenyl)-1-phenylurea
Urea,N-(4-nitrophenyl)-N'-phenyl-
Urea,N-methyl-N'-(4-nitrophenyl)-N-phenyl-

Related Compounds

4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
2-Amino-4-(2-nitrophenyl)butyric acid
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
4-Methyl-2-[(4-methylpyrimidin-2-yl)disulfanyl]pyrimidine
tert-Butyl-DL-alanine