Bis(dimethylamino)methane

Suppliers

Names

[ CAS No. ]:
51-80-9

[ Name ]:
Bis(dimethylamino)methane

[Synonym ]:
EINECS 200-124-7
TETRAMETHYL METHYLENEDIAMINE
Dimethyl[(dimethylamino)methyl]amine
Tetramethylmethanediamine
N,N,N',N'-tetramethylmethylenediamine
N,N,N,N-Tetramethyldiaminomethane
NA 9069
2,4-dimethyl-2,4-diazapentane
N,N,N′,N′-Tetramethylmethylenediamine
tetramethyldiaminomethane
N,N,N‘,N‘-Tetramethyldiaminomethane
MFCD00008328
Bis(dimethylamino)methane
((CH3)2N)2CH2
1N1&1N1&1
bis-dimethylamino-methane
bis(N,N-dimethylamino)methane
Methanediamine, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethylmethanediamine
Methylenebis(dimethylamine)
N,N,N',N'-tetramethyl-diaminomethane
N,N,N',N'-Tetramethyldiaminomethane

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
82.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-55°C

[ Molecular Formula ]:
C5H14N2

[ Molecular Weight ]:
102.178

[ Flash Point ]:
-12.8±0.0 °C

[ Exact Mass ]:
102.115700

[ PSA ]:
6.48000

[ LogP ]:
0.05

[ Vapour Pressure ]:
78.4±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.433

[ Storage condition ]:
Flammables area

[ Stability ]:
Stable, but highly flammable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents, carbon dioxide.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PA6700000
CHEMICAL NAME :
Methanediamine, N,N,N',N'-tetramethyl-
CAS REGISTRY NUMBER :
51-80-9
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H14-N2
MOLECULAR WEIGHT :
102.21
WISWESSER LINE NOTATION :
1N1&1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,734,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Highlyflammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S26-S36/37/39-S45

[ RIDADR ]:
UN 2733 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
PA6700000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formaldehyde
  • Dimethylamine
  • 1-chloro-1-methoxy-3,3-dimethylurea
  • dimethylaminomethanol
  • N,N-Dimethylformamide
  • CHLORODIMETHYLAMINE
  • Dichloromethane
  • 2,6-Di-tert-Butyl-4-(dimethylamino)methylphenol
  • tetra-N-ethyl-2-methyl-2-nitro-propanediyldiamine
  • Diethyl ether

DownStream

  • 3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one
  • 1-[3-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one
  • 1-(4-methoxyphenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one
  • 1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one
  • 1-thiophen-2-yl-2-(1,2,4-triazol-1-yl)prop-2-en-1-one
  • 1-(furan-2-yl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one
  • 1-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one
  • 1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one
  • 1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-3-methylbenzimidazol-2-one
  • 1-(4-phenylphenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one

Related Compounds

  • ethoxy-bis(dimethylamino)methane
  • Methoxy-bis(dimethylamino)methane
  • tert-butoxybis(dimethylamino)methane
  • tert-butoxy-bis(dimethylamino)methane
  • bis(dimethylamino)chlorophosphine
  • bis(dimethylamino)-methyl-(1,4,7,10-tetraoxa-13-azacyclopentadec-13-yl )phosphanium iodide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-(2-Chloroethyl)-1-methyl-1H-pyrrole
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide