2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE

Suppliers

Names

[ CAS No. ]:
51003-83-9

[ Name ]:
2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE

[Synonym ]:
2-Butyl-5,6-methylenedioxyindene-1-dimethylammonium hydrochloride
2-n-Butyl-3-dimethylamino-5,6-methylenedioxyindenehydrochloride
bu-MDI
bu-MDI HCl

Chemical & Physical Properties

[ Density]:
1.13g/cm3

[ Boiling Point ]:
367.6ºC at 760 mmHg

[ Molecular Formula ]:
C16H22ClNO2

[ Molecular Weight ]:
295.80400

[ Flash Point ]:
126.5ºC

[ Exact Mass ]:
295.13400

[ PSA ]:
21.70000

[ LogP ]:
4.40720

[ Index of Refraction ]:
1.581

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK8926000
CHEMICAL NAME :
5H-Indeno(5,6-d)-1,3-dioxole, 6-butyl-5-dimethylamino-, hydrochloride
CAS REGISTRY NUMBER :
51003-83-9
LAST UPDATED :
199606
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C16-H21-N-O2.Cl-H
MOLECULAR WEIGHT :
295.84
WISWESSER LINE NOTATION :
T C565 DO FO EH JHJ JN1&1 K4 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Gastrointestinal - decreased motility or constipation
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
185 mg/kg
TOXIC EFFECTS :
Gastrointestinal - decreased motility or constipation
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Gastrointestinal - decreased motility or constipation
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
735 mg/kg/4W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
647 mg/kg/2W-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979

Related Compounds

  • 5-((3,3-Difluoroazetidin-1-yl)methyl)-4-methylthiazole
  • N-[(6-cyclopropylpyridin-3-yl)methyl]cyclobutanecarboxamide
  • 3-[(3-Methylphenyl)methyl]bicyclo[1.1.1]pentan-1-amine
  • 1-[1-(Oxane-4-carbonyl)azetidin-3-yl]pyrrolidine
  • 3-(2,6-Dimethylphenyl)bicyclo[1.1.1]pentan-1-amine
  • 4-Cyclopentanecarbonyl-1-(5-fluoropyrimidin-2-yl)piperazin-2-one
  • 4-(Thieno[3,2-d]pyrimidin-4-yl)-1,4-oxazepane
  • N-(cyclopropylmethyl)-3-methylpyrazin-2-amine hydrochloride
  • 4-(1-methyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydroisoquinoline dihydrochloride
  • N-(2,4-dimethoxybenzyl)-7-oxaspiro[3.5]nonan-1-amine hydrochloride
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.