3,4-Dichloro-isocoumarin

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Names

[ CAS No. ]:
51050-59-0

[ Name ]:
3,4-Dichloro-isocoumarin

[Synonym ]:
3,4-dichloroisochromen-1-one
3,4-Dichloro-2-benzopyran-1-one 3,4-DCI
MFCD00036960

Chemical & Physical Properties

[ Density]:
1.53 g/cm3

[ Boiling Point ]:
304.7ºC at 760 mmHg

[ Molecular Formula ]:
C9H4Cl2O2

[ Molecular Weight ]:
215.03300

[ Flash Point ]:
136.6ºC

[ Exact Mass ]:
213.95900

[ PSA ]:
30.21000

[ LogP ]:
3.09980

[ Index of Refraction ]:
1.627

[ Storage condition ]:
2-8℃

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

Articles

Regulatory T cells require TCR signaling for their suppressive function.

J. Immunol. 194 , 4362-70, (2015)

Regulatory T cells (Tregs) are a subset of CD4(+) T cells that maintain immune tolerance in part by their ability to inhibit the proliferation of conventional CD4(+) T cells (Tconvs). The role of the ...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Polarized granzyme release is required for antigen-driven transendothelial migration of human effector memory CD4 T cells.

J. Immunol. 193(12) , 5809-15, (2014)

Human effector memory CD4 T cells may transmigrate across endothelial cell (EC) monolayers either in response to inflammatory chemokines or in response to TCR recognition of Ag presented on the surfac...


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Related Compounds

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  • 3,4-dichloro-1-methylquinolin-2-one
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  • (3,4-Dichloro-phenyl)-carbamic acid 1-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-ethyl ester
  • 3,4-Dichloro-2-naphthalenamine
  • 3,4-dichloro phenyl glycine methyl ester
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
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  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
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  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde