5-METHOXYMETHYL-2'-DEOXYURIDINE
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Names
[ CAS No. ]:
5116-22-3
[ Name ]:
5-METHOXYMETHYL-2'-DEOXYURIDINE
[Synonym ]:
5-Methoxymethyl-2'-deoxyuridine
Uridine,2'-deoxy-5-methoxymethyl
5-methoxymethyldeoxyuridine
MMUdR
Methoxymethyl deoxyuridine
Chemical & Physical Properties
[ Density]:
1.427g/cm3
[ Molecular Formula ]:
C11H16N2O6
[ Molecular Weight ]:
272.25500
[ Exact Mass ]:
272.10100
[ PSA ]:
113.78000
[ Index of Refraction ]:
1.565
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YU7900000
- CHEMICAL NAME :
- Uridine, 2'-deoxy-5-methoxymethyl-
- CAS REGISTRY NUMBER :
- 5116-22-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C11-H16-N2-O6
- MOLECULAR WEIGHT :
- 272.29
- WISWESSER LINE NOTATION :
- T6NVMVJ E1O1 A- ET5OTJ B1Q CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 gm/kg/15D-I
- TOXIC EFFECTS :
- Liver - other changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 256 mg/L
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 86,180,1986