5-Hydroxymethyl-2'-deoxyuridine

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Names

[ CAS No. ]:
5116-24-5

[ Name ]:
5-Hydroxymethyl-2'-deoxyuridine

[Synonym ]:
1-(2-Deoxypentofuranosyl)-5-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxypentofuranosyl)-5-(hydroxymethyl)-
5-HMdU HMdUdr
1-(2-deoxypentofuranosyl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
5-HYDROXYMETHYL-2'-DEOXYURIDINE

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
401.48°C (rough estimate)

[ Melting Point ]:
176-179 °C

[ Molecular Formula ]:
C10H14N2O6

[ Molecular Weight ]:
258.228

[ Exact Mass ]:
258.085175

[ PSA ]:
124.78000

[ LogP ]:
-1.49

[ Index of Refraction ]:
1.610

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7600000
CHEMICAL NAME :
Uridine, 2'-deoxy-5-(hydroxymethyl)-
CAS REGISTRY NUMBER :
5116-24-5
LAST UPDATED :
199709
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C10-H14-N2-O6
MOLECULAR WEIGHT :
258.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 gm/kg/15D-I
TOXIC EFFECTS :
Gastrointestinal - other changes Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
4 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 373,125,1997

Safety Information

[ Risk Phrases ]:
24/25

[ Safety Phrases ]:
24/25

[ WGK Germany ]:
3

[ RTECS ]:
YU7600000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-hydroxymethyl-2'-deoxyuridine-5'-triphosphate
  • 5-hydroxymethyl-2'-deoxyuridine-5'-monophosphate
  • 3',5'-bis(O-tert-butyldimethylsilyl)-5-hydroxymethyl-2'-deoxyuridine
  • 5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine
  • 5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine
  • 5-hydroxymethyl-2'-deoxycytidine-5'-triphosphate
  • N-ME-L-Norleucine hydrochloride
  • 3-(4-Bromophenyl)-1-propylpyrazole HCl
  • (R)-tert-butyl (1-(benzo[d]isothiazol-3-yl)pyrrolidin-3-yl)carbamate
  • Ethyl 4-(2-aminophenyl)benzoate hydrochloride
  • Ethyl 4-(4-aminophenyl)benzoate hydrochloride
  • H-L-Arg-anbaipr 2hcl
  • 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline trihydrochloride
  • 5-Chloro-2-(4-methylpiperazinomethyl)phenylboronic acid pinacol ester
  • 2-(6,7-dimethoxy-4-oxoquinazolin-3(4H)-yl)-N-[1-(2-methylpropyl)-1H-indol-4-yl]acetamide
  • (+)-1-(4-Cyanobenzyl)-3-(S)-fluoro-4-(S)-aminopiperidine dihydrochloride
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