Acetoin
Suppliers
Names
[ CAS No. ]:
513-86-0
[ Name ]:
Acetoin
[Synonym ]:
1-ethoxy-2-methyl-1-methylselanyl-propene
Dimethylketol
Acetylmethylcarbinol (May exist as crystalline dimer)
3-hydroxy-2-oxobutane
EINECS 208-174-1
Acetoin
3-Hydroxybutan-2-one
QY1&V1
2-Butanone, 3-hydroxy-
2-hydroxybutan-3-one
3-Hydroxy-2-butanone
dimethylketene O-ethyl Se-methyl selenoacetal
acetylmethylcarbino
Acetoin (May exist as crystalline dimer)
MFCD00004521
Acetyl methyl carbinol
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
145.4±8.0 °C at 760 mmHg
[ Melting Point ]:
15 °C (monomer)
[ Molecular Formula ]:
C4H8O2
[ Molecular Weight ]:
88.105
[ Flash Point ]:
49.7±11.0 °C
[ Exact Mass ]:
88.052429
[ PSA ]:
37.30000
[ LogP ]:
-0.43
[ Vapour Pressure ]:
1.9±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.408
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EL8790000
- CHEMICAL NAME :
- 2-Butanone, 3-hydroxy-
- CAS REGISTRY NUMBER :
- 513-86-0
- BEILSTEIN REFERENCE NO. :
- 0385636
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C4-H8-O2
- MOLECULAR WEIGHT :
- 88.12
- WISWESSER LINE NOTATION :
- QY1&V1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,509,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,509,1979
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,509,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,509,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 66 gm/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - normocytic anemia Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 10,131,1972 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12600 mg/kg
- SEX/DURATION :
- male 42 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 10,131,1972
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H315-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R10;R36/38
[ Safety Phrases ]:
S26-S36-S36/37
[ RIDADR ]:
UN 2621 3/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
EL8790000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2914400090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914400090
[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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