2-dimethylamino-1-(1-ethylindol-3-yl)ethanol

Suppliers

Names

[ CAS No. ]:
5135-83-1

[ Name ]:
2-dimethylamino-1-(1-ethylindol-3-yl)ethanol

[Synonym ]:
1-(1-Aethyl-indol-3-yl)-2-dimethylamino-aethanol
1-(1-ethyl-indol-3-yl)-2-dimethylamino-ethanol

Chemical & Physical Properties

[ Density]:
1.06g/cm3

[ Boiling Point ]:
395.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₂₀N₂O

[ Molecular Weight ]:
232.32100

[ Flash Point ]:
193.1ºC

[ Exact Mass ]:
232.15800

[ PSA ]:
28.40000

[ LogP ]:
2.25620

[ Index of Refraction ]:
1.559

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL9485600

CHEMICAL NAME :: Indole-3-methanol, alpha-((dimethylamino)methyl)-1-ethyl-

CAS REGISTRY NUMBER :: 5135-83-1

BEILSTEIN REFERENCE NO. :: 0192669

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C14-H20-N2-O

MOLECULAR WEIGHT :: 232.36

WISWESSER LINE NOTATION :: T56 BNJ B2 DYQ1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 233 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 133 mg/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section Kidney, Ureter, Bladder - urine volume increased

REFERENCE :: FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 6,75,1963

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Indole
indole-3-glyoxylyl chloride
1H-Indole-3-acetamide,N,N-dimethyl-α-oxo-

DownStream

Related Compounds

2-(dimethylamino)-1-(1-hexylindol-3-yl)ethanol
U 5092
alpha-((Dimethylamino)methyl)-1-isopropylindole-3-methanol
2-dimethylamino-1-(3-methoxyphenanthren-9-yl)ethanol
SaRI 59-801
ASINEX-REAG BAS 12968509
6-Bromo-3-phenyl-3,4-dihydroquinolin-2(1H)-one
1-Methylcyclohexane-1,2,3-triol
3,4-Dihydro-5,7-dimethoxy-2-phenyl-2H-1-benzopyran-4-ol
(2-Amino-4-methyl-oxazol-5-yl)-(4-nitrophenyl)-methanol
1,2-Benzenedicarbonitrile, 4,5-dichloro-3,6-dihydroxy-, ion(2-)
3,3-dimethyl-1-tosyl-2,3-dihydroquinolin-4(1H)-one
Epi-conferdione
O-(2-Chloroethyl)-L-serine
4-(Chloromethyl)cyclopent-1-ene
(3S)-4-methylpent-1-yn-3-amine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.