6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

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Names

[ CAS No. ]:
51513-80-5

[ Name ]:
6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

[Synonym ]:
(2,5-dioxopyrrolidin-1-yl) 6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate
Boc-6-Ahx-OSu
6-(Boc-amino)caproic acid N-succinimidyl ester (6-(Boc-amino)hexanoic acid N-succinimidyl ester
6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Melting Point ]:
86-90ºC

[ Molecular Formula ]:
C15H24N2O6

[ Molecular Weight ]:
328.36100

[ Exact Mass ]:
328.16300

[ PSA ]:
102.01000

[ LogP ]:
2.00750

[ Index of Refraction ]:
1.507

[ Water Solubility ]:
Very slightly soluble (0.95 g/L) (25 ºC)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Precursor

  • N-Hydroxysuccinimide
  • Boc-6-aminohexanoic acid
  • N,N'-Disuccinimidyl carbonate
  • 6-Aminocaproic acid
  • Di-tert-butyl dicarbonate
  • Di-tert-butyl carbonate
  • Carbonazidic acid,1,1-dimethylethyl ester

DownStream

  • Benextramine
  • 6-amino-N-[(3-oxo-1,2-oxazol-5-yl)methyl]hexanamide
  • 1,8-diazacyclotetradecane-2,9-dione

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

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J. Pept. Res. 53 , 109, (1999)

We synthesized short chromogenic peptidyl-Arg-p-nitroanilides containing either (Galbeta)Ser or (Glcalpha,beta)Tyr at P2 or P3 sites as well as O-acetylated sugar moieties and studied their hydrolysis...

An efficient stereoselective synthesis of 6-alpha-aminoestradiol: preparation of estradiol fluorescent probes.

Steroids 62 , 462, (1997)

6-Oxoestradiol (2) was protected as its bis[(2-trimethylsilylethoxy)methyl] ether (4) and converted to the corresponding oxime (4). The oxime (4) on reduction with zinc in ethanol afforded the bis-SEM...


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Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-[bis(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]acetamide
  • tert-butyl 2-(aminomethyl)-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(4-methanesulfonylpiperazin-1-yl)-4-oxobutanoic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • tert-butyl N-[3-amino-2-(trifluoromethyl)propyl]-N-(propan-2-yl)carbamate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide