6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

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Names

[ CAS No. ]:
51513-80-5

[ Name ]:
6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

[Synonym ]:
(2,5-dioxopyrrolidin-1-yl) 6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate
Boc-6-Ahx-OSu
6-(Boc-amino)caproic acid N-succinimidyl ester (6-(Boc-amino)hexanoic acid N-succinimidyl ester
6-[[(1,1-Dimethylethoxy)carbonyl]amino]hexanoic acid 2,5-dioxo-1-pyrrolidinyl ester

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Melting Point ]:
86-90ºC

[ Molecular Formula ]:
C15H24N2O6

[ Molecular Weight ]:
328.36100

[ Exact Mass ]:
328.16300

[ PSA ]:
102.01000

[ LogP ]:
2.00750

[ Index of Refraction ]:
1.507

[ Water Solubility ]:
Very slightly soluble (0.95 g/L) (25 ºC)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Precursor

  • N-Hydroxysuccinimide
  • Boc-6-aminohexanoic acid
  • N,N'-Disuccinimidyl carbonate
  • 6-Aminocaproic acid
  • Di-tert-butyl dicarbonate
  • Di-tert-butyl carbonate
  • Carbonazidic acid,1,1-dimethylethyl ester

DownStream

  • Benextramine
  • 6-amino-N-[(3-oxo-1,2-oxazol-5-yl)methyl]hexanamide
  • 1,8-diazacyclotetradecane-2,9-dione

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Chromogenic and fluorogenic glycosylated and acetylglycosylated peptides as substrates for serine, thiol and aspartyl proteases.

J. Pept. Res. 53 , 109, (1999)

We synthesized short chromogenic peptidyl-Arg-p-nitroanilides containing either (Galbeta)Ser or (Glcalpha,beta)Tyr at P2 or P3 sites as well as O-acetylated sugar moieties and studied their hydrolysis...

An efficient stereoselective synthesis of 6-alpha-aminoestradiol: preparation of estradiol fluorescent probes.

Steroids 62 , 462, (1997)

6-Oxoestradiol (2) was protected as its bis[(2-trimethylsilylethoxy)methyl] ether (4) and converted to the corresponding oxime (4). The oxime (4) on reduction with zinc in ethanol afforded the bis-SEM...


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Related Compounds

  • 2-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)phenoxy]-N-[3-(4-morpholinyl)propyl]acetamide
  • methyl [6-chloro-9-(4-methoxybenzyl)-4-methyl-2-oxo-9,10-dihydro-2H,8H-chromeno[8,7-e][1,3]oxazin-3-yl]acetate
  • 3-(4-Methoxyphenyl)-2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl dimethylcarbamate
  • 3-{6-[(2-methylprop-2-en-1-yl)oxy]-4-oxo-2-{(E)-2-[4-(propan-2-yl)phenyl]ethenyl}quinazolin-3(4H)-yl}benzoic acid
  • 6,8-difluoro-1-(2-fluoroethyl)-4-oxo-N-(pyridin-2-ylmethyl)-7-[(pyridin-2-ylmethyl)amino]-1,4-dihydroquinoline-3-carboxamide
  • 3-Amino-1-(4-bromo-2-fluorophenyl)thiourea
  • 5-[(dimethylamino)methyl]-6-hydroxy-3-(4-methoxyphenyl)-2-methylquinazolin-4(3H)-one
  • 8-allyl-7-hydroxy-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
  • N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methyl-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
  • 2-(4-methoxybenzyl)-9-(3-methoxyphenyl)-8-methyl-2,3-dihydro-1H-[1,3]oxazino[5,6-f]quinazolin-10(9H)-one
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