GW 803430

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Names

[ CAS No. ]:
515141-51-2

[ Name ]:
GW 803430

[Synonym ]:
GW-3430
UNII-4R0136W1PR
Guggulsterone
QCR-157

Chemical & Physical Properties

[ Molecular Formula ]:
C25H24ClN3O3S

[ Molecular Weight ]:
481.99400

[ Exact Mass ]:
481.12300

[ PSA ]:
84.83000

[ LogP ]:
5.18870

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Articles

Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression.

J. Pharmacol. Exp. Ther. 329(2) , 429-38, (2009)

The mammalian neuropeptide, melanin-concentrating hormone, interacts with two G protein-coupled receptors, melanin-concentrating hormone receptor (MCHR) 1 and MCHR2; however, only MCHR1 is expressed i...

Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats.

Psychopharmacology 211(4) , 367-75, (2010)

Melanin-concentrating hormone (MCH) is involved in regulation of appetitive behaviors as well as emotional reactivity and reward, behavioral domains relevant to alcohol addiction.We evaluated the effe...


More Articles

Related Compounds

  • GW 9578
  • GW-406381
  • GW 766994
  • GW 627368
  • GW-1100
  • GW 6471