methallenestril

Suppliers

Names

[ CAS No. ]:
517-18-0

[ Name ]:
methallenestril

[Synonym ]:
3-(6-methoxynaphthalen-2-yl)-2,2-dimethyl-pentanoic acid
3-(6-methoxy-2-naphthyl)-2,2-dimethyl-valeric acid

Chemical & Physical Properties

[ Density]:
1.108g/cm3

[ Boiling Point ]:
437ºC at 760mmHg

[ Melting Point ]:
139-140ºC

[ Molecular Formula ]:
C18H22O3

[ Molecular Weight ]:
286.36500

[ Flash Point ]:
154.7ºC

[ Exact Mass ]:
286.15700

[ PSA ]:
46.53000

[ LogP ]:
4.45280

[ Index of Refraction ]:
1.572

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK0302500
CHEMICAL NAME :
2-Naphthalenepropionic acid, beta-ethyl-6-methoxy-alpha,alpha-dimethyl-
CAS REGISTRY NUMBER :
517-18-0
LAST UPDATED :
198910
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-O3
MOLECULAR WEIGHT :
286.40
WISWESSER LINE NOTATION :
L66J CY2&X1&1&VQ HO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
175 ug/kg
SEX/DURATION :
female 35 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 63,561,1958
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
75 ug/kg
SEX/DURATION :
female 30 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
RPHRA6 Recent Progress In Hormone Research. Proceedings of the Laurentian Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1947- Volume(issue)/page/year: 20,395,1964

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2H-Naphtho[1,2-b]pyran-2-one, 4-ethyl-3,4,5,6-tetrahydro-8-methoxy-3,3-dimethyl- (en)
  • 2-Naphthalenepropionic acid, .β.-ethyl-1,2,3,4-tetrahydro-6-methoxy-.α.,.α.-dimethyl-1-oxo- (en)
  • 6'-Methoxy-2'-propiononaphthone
  • 3-(6-methoxy-[2]naphthyl)-2,2-dimethyl-valeric acid ethyl ester
  • 2-Methoxynaphthalene
  • ethyl beta-ethylidene-6-methoxy-alpha,alpha-dimethylnaphthalene-2-propionate

DownStream

Related Compounds

  • 1-(5-cyanopyridin-2-yl)-N-cyclopropylpiperidine-3-carboxamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N-[4-(1,1-dioxido-1,2-thiazolidin-2-yl)phenyl]-3-(5-phenyl-1,3-oxazol-2-yl)propanamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine