Dicentrine

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Names

[ CAS No. ]:
517-66-8

[ Name ]:
Dicentrine

[Synonym ]:
(7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
Dicentrine
DICENTRINE- (+)
9,10-Dimethoxy-1,2-(methylenedioxy)-6aalpha-aporphine
o,N-Dimethyllitseferine
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (S)-
d-Dicentrine
(7aS)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
1,2-(Methylenedioxy)-9,10-dimethoxy-6aalpha-aporphine
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aS)-
1,2-Methylenedioxy-9,10-dimethoxyaporphine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
480.7±45.0 °C at 760 mmHg

[ Melting Point ]:
177-178ºC

[ Molecular Formula ]:
C20H21NO4

[ Molecular Weight ]:
339.385

[ Flash Point ]:
142.7±25.9 °C

[ Exact Mass ]:
339.147064

[ PSA ]:
40.16000

[ LogP ]:
3.98

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.616

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CE0455000
CHEMICAL NAME :
6a-alpha-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)-
CAS REGISTRY NUMBER :
517-66-8
BEILSTEIN REFERENCE NO. :
0095476
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H21-N-O4
MOLECULAR WEIGHT :
339.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990

Synthetic Route

Precursor & DownStream

Precursor

  • Actinodaphnine
  • Nordicentrine
  • methyl iodide
  • diazomethane
  • Formaldehyde
  • litseferine

DownStream

  • 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7-dihydro-10,11-dimethoxy-7-Methyl-

Related Compounds

  • Dicentrine
  • DICENTRINE HYDROCHLORIDE
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 4-Azido-5-chloropyridine-3-carbaldehyde
  • (2S)-1-cyclohexylpropan-2-amine hydrochloride
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine