(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Names

[ CAS No. ]:
51713-80-5

[ Name ]:
(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Chemical & Physical Properties

[ Boiling Point ]:
319.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₈ClNO₂

[ Molecular Weight ]:
243.73000

[ Flash Point ]:
146.8ºC

[ Exact Mass ]:
243.10300

[ PSA ]:
32.70000

[ LogP ]:
2.68960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX5980000

CHEMICAL NAME :: 7-Isoquinolinol, 1,2,3,4-tetrahydro-1,2-dimethyl-6-methoxy-, hydrochloride, (1R)-(-)-

CAS REGISTRY NUMBER :: 51713-80-5

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H17-N-O2.Cl-H

MOLECULAR WEIGHT :: 243.76

WISWESSER LINE NOTATION :: T66 CNT&J B1 C1 HO1 IQ &GH -1R(-)

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974

Related Compounds

4-(2,4-Dimethylbenzoyl)piperidine-1-sulfonyl fluoride
N-Methyl-N-[(8-oxo-6,7-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)methyl]sulfamoyl fluoride
2-(Trifluoromethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-7-sulfonyl fluoride
8-Acetamido-1,2,3,4-tetrahydroisoquinoline-2-sulfonyl fluoride
3-(1-Methylbenzimidazol-2-yl)azetidine-1-sulfonyl fluoride
N-[(2-Methoxy-4,6-dimethylpyridin-3-yl)methyl]-N-methylsulfamoyl fluoride
tert-butyl N-[1-(2-ethylphenyl)-2-(prop-2-enamido)ethyl]carbamate
N-(1,3-Benzodioxol-5-ylmethyl)-N-(1-methylcyclopentyl)prop-2-enamide
tert-butyl 3-[N-(2,2,2-trifluoroethyl)prop-2-enamido]piperidine-1-carboxylate
N-[(2R,3S)-2-(4-Chlorophenyl)-1-methyl-5-oxopyrrolidin-3-yl]prop-2-enamide

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