(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Names

[ CAS No. ]:
51713-80-5

[ Name ]:
(1R)-6-methoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol,chloride

Chemical & Physical Properties

[ Boiling Point ]:
319.1ºC at 760 mmHg

[ Molecular Formula ]:
C12H18ClNO2

[ Molecular Weight ]:
243.73000

[ Flash Point ]:
146.8ºC

[ Exact Mass ]:
243.10300

[ PSA ]:
32.70000

[ LogP ]:
2.68960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5980000
CHEMICAL NAME :
7-Isoquinolinol, 1,2,3,4-tetrahydro-1,2-dimethyl-6-methoxy-, hydrochloride, (1R)-(-)-
CAS REGISTRY NUMBER :
51713-80-5
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H17-N-O2.Cl-H
MOLECULAR WEIGHT :
243.76
WISWESSER LINE NOTATION :
T66 CNT&J B1 C1 HO1 IQ &GH -1R(-)

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,134,1974

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-(6-(pyrrolidin-1-yl)pyrimidin-4-yl)-2-(o-tolyl)acetamide
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide