Dimethoxanate hydrochloride

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Names

[ CAS No. ]:
518-63-8

[ Name ]:
Dimethoxanate hydrochloride

[Synonym ]:
Cothera
EINECS 208-255-1
Dimethoxanate HCl
DIMETHOXANATE HYDROCHLORIDE
Perlatos
Dimetoxanate hydrochloride
Dimethoxanate monohydrochloride
Tussizid

Chemical & Physical Properties

[ Boiling Point ]:
494ºC at 760 mmHg

[ Molecular Formula ]:
C19H23ClN2O3S

[ Molecular Weight ]:
394.91600

[ Flash Point ]:
252.6ºC

[ Exact Mass ]:
394.11200

[ PSA ]:
67.31000

[ LogP ]:
4.87110

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN7525000
CHEMICAL NAME :
Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride
CAS REGISTRY NUMBER :
518-63-8
LAST UPDATED :
199106
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H22-N2-O3-S.Cl-H
MOLECULAR WEIGHT :
394.95
WISWESSER LINE NOTATION :
T C666 BN ISJ BVO2O2N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,43,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
29ZVAB "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969 Volume(issue)/page/year: -,43,1969

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-[2-(Dimethylamino)ethoxy]ethanol
  • 10H-Phenothiazine-10-carbonyl chloride

DownStream

Related Compounds

  • Dimethoxanate
  • Triprolidine hydrochloride
  • Elacridar hydrochloride
  • Tyrocidine, hydrochloride
  • dodecylamine hydrochloride
  • Minoxidil hydrochloride
  • 4-(3,5-dimethyl-1H-pyrazol-1-yl)-2-methyl-6-{4-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]piperazin-1-yl}pyrimidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-{4-[2-(Ethylamino)pyrimidin-4-yl]piperazin-1-yl}-1lambda6,2-benzothiazole-1,1-dione
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • (2R)-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methyloxolan-3-yl]formamido}-3-hydroxypropanoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde