Luminol
Suppliers
Names
[ CAS No. ]:
521-31-3
[ Name ]:
Luminol
[Synonym ]:
EINECS 208-309-4
LUMINOL
5-Amino-2,3-dihydrophthalazine-1,4-dione
5-Amino-2,3-dihydro-1,4-phthalazinedione
Dia0003Luminol
o-Aminophthalhydride
LuminolFreeAcid
phthalazinedione
3-aminophthalic hydrazide
Diogenes Reagent
3-Aminophthaloylhydrazine
MFCD00006890
RARECHEM AH BS 0053
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
621.9ºC at 760 mmHg
[ Melting Point ]:
>300 °C(lit.)
[ Molecular Formula ]:
C8H7N3O2
[ Molecular Weight ]:
177.160
[ Flash Point ]:
329.9ºC
[ Exact Mass ]:
177.053833
[ PSA ]:
91.74000
[ LogP ]:
-0.71
[ Index of Refraction ]:
1.649
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents. Emits light on reaction with oxidizers.
[ Water Solubility ]:
<0.1 g/100 mL at 19 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TH8890060
- CHEMICAL NAME :
- 1,4-Phthalazinedione, 5-amino-2,3-dihydro-
- CAS REGISTRY NUMBER :
- 521-31-3
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H7-N3-O2
- MOLECULAR WEIGHT :
- 177.18
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- CHROAU Chromosoma. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1939- Volume(issue)/page/year: 99,360,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7070 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36/37-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TH8890060
[ HS Code ]:
29339990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Plant Cell 26(10) , 4171-87, (2014)
In Arabidopsis thaliana, responses to pathogen-associated molecular patterns (PAMPs) are mediated by cell surface pattern recognition receptors (PRRs) and include the accumulation of reactive oxygen s...
Oncotarget 6(9) , 6877-86, (2015)
High doses of the organic nitrate glyceryl trinitrate (GTN), a nitric oxide (NO) donor, are known to trigger apoptosis in human cancer cells. Here, we show that such a cytotoxic effect can be obtained...
J. Appl. Physiol. 117(3) , 307-15, (2014)
Myoglobin (Mb) is an oxygen-binding muscular hemeprotein regulated via Ca(2+)-signaling pathways involving calcineurin (CN), with Mb increases attributed to hypoxia, exercise, and nitric oxide. Here, ...