2-(1-hydroxysilinan-1-yl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine

Names

[ CAS No. ]:
521059-17-6

[ Name ]:
2-(1-hydroxysilinan-1-yl)-2-(4-methoxyphenyl)-N,N-dimethylethanamine

[Synonym ]:
Rac-Sila-Venlafaxine
Silacyclohexan-1-ol,1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]

Chemical & Physical Properties

[ Molecular Formula ]:
C16H27NO2Si

[ Molecular Weight ]:
293.47700

[ Exact Mass ]:
293.18100

[ PSA ]:
32.70000

[ LogP ]:
3.09680

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-chloro-1-[1-(4-methoxyphenyl)vinyl]-1-silacyclohexane
  • Dimethylamine
  • 1,1-dichlorosilinane
  • 1-methoxy-1-(2,4,6-trimethoxyphenyl)silinane
  • 1-[1-(4-methoxyphenyl)vinyl]-1-(2,4,6-trimethoxyphenyl)-1-silacyclohexane

DownStream

Related Compounds

  • 1-[2-(1H-benzimidazol-2-yl)ethyl]-5-imino-4-(4-phenyl-1,3-thiazol-2-yl)-2,5-dihydro-1H-pyrrol-3-ol
  • 4-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-imino-1-[(1-methyl-1H-pyrrol-2-yl)methyl]-2,5-dihydro-1H-pyrrol-3-ol
  • 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-imino-1-[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]-2,5-dihydro-1H-pyrrol-3-ol
  • 5-cyclopentyloxy-1H-indole-2-carboxylic acid
  • 5-amino-1-(3-hydroxy-2H-1,4-benzoxazin-6-yl)-4-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1,2-dihydro-3H-pyrrol-3-one
  • 5-imino-1-(6-methoxy-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-4-(4-phenyl-1,3-thiazol-2-yl)-2,5-dihydro-1H-pyrrol-3-ol
  • {3-[4-hydroxy-2-imino-3-(4-phenyl-1,3-thiazol-2-yl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methoxyphenyl}(piperidin-1-yl)methanone
  • 1-{[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-imino-2,5-dihydro-1H-pyrrol-3-ol
  • 4-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-5-imino-1-{3-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]propyl}-2,5-dihydro-1H-pyrrol-3-ol
  • 4-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-imino-1-[2-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]-2,5-dihydro-1H-pyrrol-3-ol
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