1-Benzyl-2,5-dimethylserotonin hydrochloride

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Names

[ CAS No. ]:
525-02-0

[ Name ]:
1-Benzyl-2,5-dimethylserotonin hydrochloride

[Synonym ]:
1-Benzyl-2,5-dimethylserotonin hydrochloride
Benanserin HCl
Benzyl antiserotonin
1-Benzyl-2-methyl-5-methoxytryptamine hydrochloride
Serotonin benzyl analog
Woolley's antiserotonin
Benanserin hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
494.7ºC at 760 mmHg

[ Molecular Formula ]:
C19H23ClN2O

[ Molecular Weight ]:
330.85200

[ Flash Point ]:
253ºC

[ Exact Mass ]:
330.15000

[ PSA ]:
40.18000

[ LogP ]:
5.01010

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL4025000
CHEMICAL NAME :
Indole, 3-(2-aminoethyl)-1-benzyl-5-methoxy-2-methyl-, monohydrochloride
CAS REGISTRY NUMBER :
525-02-0
LAST UPDATED :
199009
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H22-N2-O.Cl-H
MOLECULAR WEIGHT :
330.89
WISWESSER LINE NOTATION :
T56 BNJ B1R& C1 D2Z GO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,819,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 18,833,1963 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
70 mg/kg
SEX/DURATION :
female 8-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
REFERENCE :
PEDIAU Pediatrics. (American Academy of Pediatrics, P.O. Box 1034, Evanston, IL 60204) V.1- 1948- Volume(issue)/page/year: 27,318,1961

Related Compounds

  • 1-BENZYL-2,5-BIS(CHLOROMETHYL)PIPERIDINE HYDROCHLORIDE
  • 1-BENZYL-2,5-BIS(CHLOROMETHYL)PYRROLIDINE HYDROCHLORIDE
  • 1-BENZYL-2,5-BIS(CHLOROMETHYL)-3-METHYLPYRROLIDINE HYDROCHLORIDE
  • 1-benzyl-2,5-dimethyl-N-phenylpiperidin-4-imine
  • 1-BENZYL-2,5-DIMETHYL-1H-PYRROLE-3-CARBALDEHYDE
  • 1-BENZYL-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID
  • Methyl 2-{[(3-methylfuran-2-yl)methyl]sulfanyl}acetate
  • Methyl 3-{[(3-methylfuran-2-yl)methyl]sulfanyl}prop-2-enoate
  • rac-(3R,4S)-1-methyl-4-(1-methyl-1H-imidazol-5-yl)pyrrolidin-3-amine, trans
  • rac-2-methoxy-N-[(3R,4S)-4-(1-methyl-1H-pyrazol-5-yl)pyrrolidin-3-yl]acetamide, trans
  • rac-tert-butyl (3R,4S)-3-(aminomethyl)-4-(1-methyl-1H-imidazol-5-yl)pyrrolidine-1-carboxylate, trans
  • 2-(4-Hydroxypyrrolidin-3-yl)acetamide hydrochloride
  • 1-[3-amino-4-(4-methoxyphenyl)pyrrolidin-1-yl]-3-(3,5-dimethyl-1H-pyrazol-1-yl)propan-1-one dihydrochloride
  • 1-(5,5-Dimethyl-4,5-dihydro-1,2-oxazole-3-carbonyl)-4-(4-methoxyphenyl)pyrrolidin-3-amine hydrochloride
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylate
  • 3-[3-(Trifluoromethyl)pyridin-2-yl]furan-2-sulfonyl fluoride
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