osalmid

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Names

[ CAS No. ]:
526-18-1

[ Name ]:
osalmid

[Synonym ]:
MFCD00020026
bilene
osalmid
bilocol
2-Hydroxy-N-(4-hydroxyphenyl)benzamide
Qsalmid
auxobil
EINECS 208-385-9
LOIRD
2-Hydroxy-N-(4-Hydroxy Phenyl)Benzamide
driol
phps
l1718
Benzamide, 2-hydroxy-N-(4-hydroxyphenyl)-
4'-HYDROXYSALICYLANILIDE
Oksafenamide
enidran
N-Salicoylaminophenol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
350.8±27.0 °C at 760 mmHg

[ Melting Point ]:
179ºC

[ Molecular Formula ]:
C₁₃H₁₁NO₃

[ Molecular Weight ]:
229.231

[ Flash Point ]:
165.9±23.7 °C

[ Exact Mass ]:
229.073898

[ PSA ]:
69.56000

[ LogP ]:
2.53

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.711

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VN8830000

CHEMICAL NAME :: Salicylanilide, 4'-hydroxy-

CAS REGISTRY NUMBER :: 526-18-1

BEILSTEIN REFERENCE NO. :: 2941480

LAST UPDATED :: 199806

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H11-N-O3

MOLECULAR WEIGHT :: 229.25

WISWESSER LINE NOTATION :: QR BVMR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6702 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,159,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1484 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,290,1995

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,159,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1050 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 22,235,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 517 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,159,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03234

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
26-36/37

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Aminophenol
Salicylic acid
Phenyl salicylate

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

Tetrasodium;6-[(2,4-diaminophenyl)diazenyl]-3-[[4-[4-[[7-[(2,4-diamino-5-sulfonatophenyl)diazenyl]-1-hydroxy-3-sulfonatonaphthalen-2-yl]diazenyl]anilino]-3-sulfonatophenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonate
5-Ethoxy-4-hydroxy-3-[2-[4-(6-methyl-2-benzothiazolyl)phenyl]diazenyl]-2,7-naphthalenedisulfonic acid
2-Naphthalenesulfonic acid, 3-((4-((4-amino-2-sulfophenyl)azo)-6-sulfo-1-naphthalenyl)azo)-7-((6-((4-((4-amino-2-sulfophenyl)azo)-7-sulfo-1-naphthalenyl)azo)-5-hydroxy-7-sulfo-2-naphthalenyl)amino)-4-hydroxy-, hexasodium salt
(s)-1-Amino-2,3-dihydro-1h-indene-5-carboxylic acid hydrochloride
(s)-5-Bromo-4-methyl-2,3-dihydro-1h-inden-1-amine hydrochloride
1-cyclopropyl-3-Azetidinesulfonamide
1-(2-Pyridinylmethyl)-3-azetidinesulfonamide
TX58P9Y5GK
Methyl 3-fluoro-4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]pyrrolidine-3-carboxylate;hydrochloride
(2S,5R)-5-Methylpiperidine-2-carboxylic acid;hydrochloride

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