2,3-Dimethylphenol

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Names

[ CAS No. ]:
526-75-0

[ Name ]:
2,3-Dimethylphenol

[Synonym ]:
2,3-dimethyl phenol
Phenol,2,3-dimethyl
Vic-o-Xylenol
o-3-Xylenol
Xylenol
o-Xylenol
EINECS 208-395-3
Phenol, 2,3-dimethyl-
2,3-Dimethylphenol
MFCD00002227
3-Hydroxyl-o-xylene,vic.-o-Xylenol
di-methylphenol
1-Hydroxy-2,3-dimethylbenzene
2,3-Xylenol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
216.9±0.0 °C at 760 mmHg

[ Melting Point ]:
72-74ºC

[ Molecular Formula ]:
C8H10O

[ Molecular Weight ]:
122.164

[ Flash Point ]:
90.7±7.2 °C

[ Exact Mass ]:
122.073166

[ PSA ]:
20.23000

[ LogP ]:
2.40

[ Vapour density ]:
4.23 (vs air)

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.540

[ Water Solubility ]:
slightly soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE5500000
CHEMICAL NAME :
2,3-Xylenol
CAS REGISTRY NUMBER :
526-75-0
BEILSTEIN REFERENCE NO. :
1906267
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C8-H10-O
MOLECULAR WEIGHT :
122.18
WISWESSER LINE NOTATION :
QR B1 C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>85500 ug/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A180-198
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00158 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1581 No. of Facilities: 61 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 136 (estimated) No. of Female Employees: 56 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H314-H411

[ Precautionary Statements ]:
P273-P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R24/25;R34;R51/53

[ Safety Phrases ]:
S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 2261

[ WGK Germany ]:
3

[ RTECS ]:
ZE5500000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

Precursor & DownStream

Precursor

  • o-xylene
  • 1-Iodo-2,3-dimethylbenzene
  • 2,3-Dimethylaniline
  • acetic acid
  • 2,3-dimethylcyclohex-2-en-1-one
  • But-2-yne
  • BUT-3-ENOYL CHLORIDE
  • 2,3-xylyl acetate
  • 6,6-dimethylcyclohexa-2,4-dien-1-one

DownStream

  • 7-Bromoisobenzofuran-1(3H)-one
  • 2,3-DIMETHYL-PARA-ANISALDEHYDE
  • 4-Bromo-2,3-dimethylanisole
  • Benzene,2,3-bis(bromomethyl)-1,4-dimethoxy-
  • 2,3-xylyl acetate
  • 2,3-DIMETHYL-4,5-DIIODOPHENOL
  • 6-iodo-2,3-dimethyl-phenol
  • 4-Iodo-2,3-dimethylphenol
  • 1-Iodo-4-methoxy-2,3-dimethylbenzene
  • Mequinol

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Chem. Pharm. Bull. 63 , 573-8, (2015)

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Related Compounds

  • 4-Iodo-2,3-dimethylphenol
  • 6-Allyl-2,3-dimethylphenol
  • 6-Bromo-2,3-dimethylphenol
  • 4-nitro-2,3-dimethylphenol
  • 5-bromo-2,3-dimethylphenol
  • 4-ethyl-2,3-dimethylphenol
  • 4-({2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-5-yl}formamido)-3-hydroxy-3-methylbutanoic acid
  • rac-2-[(3R,4R)-1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3-methylbutanoyl}-4-methylpyrrolidin-3-yl]acetic acid
  • 2-{1-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoyl]-4-methylpyrrolidin-3-yl}acetic acid
  • 2-{1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazole-5-carbonyl]pyrrolidin-2-yl}acetic acid
  • 4-{1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-3-yl]-N-methylformamido}butanoic acid
  • (2R)-2-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-3-yl]formamido}-3-methylbutanoic acid
  • 4-[4-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-hydroxybutanoic acid
  • (2R)-2-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid
  • 5-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-4-yl]formamido}-4-methylpentanoic acid
  • 4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]-1-methyl-1H-pyrazole-3-carboxylic acid
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