Cyclo(-Asp-Phe)

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Names

[ CAS No. ]:
5262-10-2

[ Name ]:
Cyclo(-Asp-Phe)

[Synonym ]:
2-[(2S,5S)-5-benzyl-3,6-dioxopiperazin-2-yl]acetic acid
EINECS 226-075-1
MFCD00190764

Chemical & Physical Properties

[ Density]:
1.298g/cm3

[ Boiling Point ]:
667.4ºC at 760mmHg

[ Melting Point ]:
270-272ºC(lit.)

[ Molecular Formula ]:
C13H14N2O4

[ Molecular Weight ]:
262.26100

[ Flash Point ]:
357.4ºC

[ Exact Mass ]:
262.09500

[ PSA ]:
95.50000

[ LogP ]:
0.34460

[ Index of Refraction ]:
1.561

[ Storage condition ]:
-15°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Precursor & DownStream

Precursor

  • Aspartame
  • Methyl L-phenylalaninate

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Structures, sensory activity, and dose/response functions of 2,5-diketopiperazines in roasted cocoa nibs (Theobroma cacao).

J. Agric. Food Chem. 53 , 7222-7231, (2005)

The taste compounds inducing the blood-like, metallic bitter taste sensation reported recently for a dichloromethane extract prepared from roasted cocoa nibs were identified as a series of 25 diketopi...

Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study.

Brain Res. Bull. 32(6) , 667-72, (1993)

The effects of two diketopiperazines, Cyclo (His-Pro) (CHP) and Cyclo (Asp-Phe) (CAP), on striatal extracellular levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), a...


More Articles


Related Compounds

  • Cyclo(-Asp-Gly)
  • CYCLO(-ASP(OME)-ASP(OME))
  • CYCLO(-ASP-ASP)
  • CYCLO(-PHE-SER)
  • Cyclo(Phe-Pro)
  • Cyclo(Phe-Hpro)
  • 2-(4-Fluorophenyl)-5-pyrimidinol
  • 2-Propylpentane-1-thiol
  • Methyl 3-(Azepan-1-yl)butanoate
  • 1-O-tert-butyl 2-O-ethyl (2S,3S)-3-hydroxypiperidine-1,2-dicarboxylate
  • 2-(3-Methyl-2,4,5-trioxoimidazolidin-1-yl)acetic acid
  • 2,2-Dibromo-1-(3-pyridyl)ethanone
  • 3-(o-Tolyl)-1,2,4-thiadiazole-5-thiol
  • Tetracaine N-Oxide
  • Diethyl 2-[(hydroxyacetyl)amino]malonate
  • 3-(3-Chloro-4-methoxyphenyl)propanenitrile
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