2,4,6-Trimethylphenol

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Names

[ CAS No. ]:
527-60-6

[ Name ]:
2,4,6-Trimethylphenol

[Synonym ]:
2,4,6-Trimethyl-phenol
2,3-DIMETHOXYPHENETHYL ISOCYANATE
Phenol, 2,4,6-trimethyl-
Mesityl alcohol
1,3,5-Trimethylphenol
2-Hydroxymesitylene
Phenol,2,4,6-trimethyl
EINECS 208-419-2
Hydroxymesitylene
2,4,6-Trimetylofenol [Polish]
MFCD00002235
Mesitol
2,4,6-Trimethylphenol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
215.8±9.0 °C at 760 mmHg

[ Melting Point ]:
70-72 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂O

[ Molecular Weight ]:
136.191

[ Flash Point ]:
96.7±8.4 °C

[ Exact Mass ]:
136.088821

[ PSA ]:
20.23000

[ LogP ]:
2.86

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.536

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OX6590000

CHEMICAL NAME :: Mesitol

CAS REGISTRY NUMBER :: 527-60-6

BEILSTEIN REFERENCE NO. :: 1859675

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H12-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 14,301,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,201,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0455 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 75 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0455 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 93 (estimated) No. of Female Employees: 56 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H411

[ Precautionary Statements ]:
P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S24/25

[ RIDADR ]:
UN 2430 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
OX6590000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2907199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Mesitylboronic acid
2,4,6-Trimethylbromobenzene
Benzene,1,3,5-trimethyl-2-(2-propen-1-yloxy)-
Phenylacetylene
2,6-Bis(hydroxymethyl)-p-cresol
O-2,4,6-trimethylphenyl-S-methyldithiocarbonate
1,3,5-trimethyl-2-(triphenylsilyloxy)benzene
Mesitylene
MESITYLLITHIUM

DownStream

2,4,6-trimethyl-6-phenylcyclohexa-2,4-dien-1-one
2,4-dichloro-6-(2,4,6-trimethylphenoxy)-1,3,5-triazine
N,N-diethyl-2-(2,4,6-trimethylphenoxy)ethanamine
3,5-Dimethyl-4-hydroxybenzaldehyde
2,6-dimethyl-p-benzoquinone
2,5-Cyclohexadien-1-one,4-hydroxy-2,4,6-trimethyl-
4-(ethoxymethyl)-2,6-dimethyl-phenol
2-HYDROXY-3-METHYL-BENZOIC ACID
Benzenemethanol,4-hydroxy-3,5-dimethyl-
2-(2,4,6-trimethylphenyl)quinoline

Customs

[ HS Code ]: 2907199090

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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