Quisqualic acid

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Names

[ Name ]:
Quisqualic acid

[Synonym ]:
L-Alanine, 3-(3-hydroxy-5-oxo-1,2,4-oxadiazol-2(5H)-yl)-
L-Quisqualic acid
L-Alanine, 3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)-
1,2,4-Oxadiazolidine-2-propanoic acid, α-amino-3,5-dioxo-, (S)-
MFCD00069337
3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
b-(3,5-Dioxo-1,2,4-oxodiazolidin-2-yl)-L-alanine
L-(+)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid
(L)-(+)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
Quisqualic acid
3-(3-Hydroxy-5-oxo-1,2,4-oxadiazol-2(5H)-yl)-L-alanine
β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
L-Quisqualic acid,(L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoicacid
(S)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
405.9±55.0 °C at 760 mmHg

[ Melting Point ]:
185-187ºC dec.

[ Molecular Formula ]:
C₅H₇N₃O₅

[ Molecular Weight ]:
189.126

[ Flash Point ]:
199.3±31.5 °C

[ Exact Mass ]:
189.038574

[ PSA ]:
131.32000

[ LogP ]:
-1.85

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.726

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Long-term administration of the antidepressant vilazodone modulates rat brain monoaminergic systems.

Neuropharmacology 99 , 696-704, (2015)

Vilazodone has high affinity for the human 5-hydroxytryptamine1A (h5-HT1A) receptor and for the serotonin transporter (5-HTT). A previous in vivo microdialysis experiment showed that a single administ...

Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system [formula omitted]over the vesicular glutamate transporter

Bioorg. Med. Chem. Lett. 20 , 2680-3, (2010)

A panel of amino acid analogs and conformationally-restricted amino acids bearing a sulfonic acid were synthesized and tested for their ability to preferentially inhibit the obligate cysteine-glutamat...