6-bromo-3-formylchromone

Names

[ Name ]:
6-bromo-3-formylchromone

[Synonym ]:
6-BroMo-3-forMylchroMone
MFCD00191849
6-bromo-4-oxochromene-3-carbaldehyde
6-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde
6-Bromochromone-3-carboxaldehyde

Chemical & Physical Properties

[ Density]:
1.835g/cm3

[ Boiling Point ]:
365.7ºC at 760 mmHg

[ Melting Point ]:
190-193 °C(lit.)

[ Molecular Formula ]:
C₁₀H₅BrO₃

[ Molecular Weight ]:
253.04900

[ Flash Point ]:
175ºC

[ Exact Mass ]:
251.94200

[ PSA ]:
47.28000

[ LogP ]:
2.36800

[ Index of Refraction ]:
1.713

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

Bioorg. Med. Chem. 19 , 3367-71, (2011)

Series of chromone containing sulfonamides were prepared by the reaction of (un)substituted 3-formylchromones with 3-aminobenzenesulfonamide and 4-aminobenzenesulfonamide. Bovine carbonic anhydrase (b...

Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.

In Vivo 20(5) , 645-9, (2006)

Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relati...

Biological activity of 3-formylchromones and related compounds.

In Vivo 21(5) , 829-34, (2007)

Several 3-formylchromone derivatives were examined for their tumor cell-cytotoxic, anti-Helicobacter pylori, urease inhibitory and anti-HIV activity. Comparing their relative cytotoxicity against four...

2-amino-6-bromo-3-formylchromone
2-amino-6-bromo-3-formylchromone
6-bromo-3-ethyl-1-methylindazole
6-Bromo-3-chloro-2-methylpyridine
6-Bromo-3-cyano-4-methylcoumarin
6-bromo-3-[(4-chlorophenyl)methyl]-2-methoxyquinoline
6-Bromo-2,2-dimethylspiro[3.3]heptane
(1R,2S,5S)-N-Benzyl-5-propan-2-ylbicyclo[3.1.0]hexan-2-amine
(3R,5R)-5-(aminomethyl)-1-{6-[ethyl(methyl)amino]pyrimidin-4-yl}pyrrolidin-3-ol
methyl 1-[(3-aminocyclobutyl)methyl]-1H-1,2,3-triazole-4-carboxylate
2-[[(2-Methylpropan-2-yl)oxycarbonylamino]methyl]piperidine-4-carboxylic acid
Tert-butyl 2-(2-chloropyrimidin-4-yl)-2,7-diazaspiro[3.5]nonane-7-carboxylate
Tert-butyl 2-[(6-chloropyridazin-3-yl)methyl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
Tert-butyl (3aR,6aS)-2-(5-bromopyrazin-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate
Tert-butyl (3aS,6aR)-2-[(6-chloropyridazin-3-yl)methyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate
Tert-butyl 4-[(6-chloropyridazin-3-yl)methyl-methylamino]azepane-1-carboxylate

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