Piperic acid

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Names

[ Name ]:
Piperic acid

[Synonym ]:
piperinic acid
5-(3,4-methylenedioxyphenyl)-2,4-pentadienic acid
2,4-Pentadienoic acid,5-(1,3-benzodioxol-5-yl)
5-(1,3-benzodioxol-5-yl)penta-2,4-dienoic acid
piperic acid
5-(3,4-Methylenedioxyphenyl)-2,4-pentadienoic acid Piperic acid

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
427.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₁₀O₄

[ Molecular Weight ]:
218.20500

[ Flash Point ]:
171.5ºC

[ Exact Mass ]:
218.05800

[ PSA ]:
55.76000

[ LogP ]:
2.06930

[ Index of Refraction ]:
1.647

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Design, synthesis and characterization of some bioactive conjugates of curcumin with glycine, glutamic acid, valine and demethylenated piperic acid and study of their antimicrobial and antiproliferative properties.

Eur. J. Med. Chem. 43 , 1837-1846, (2008)

The monoesters of curcumin, a symmetric diphenol with valine and glycine have been prepared by a novel solid phase synthesis and its diesters with valine, glutamic acid and demethylenated piperic acid...

Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties.

Bioorg. Med. Chem. 13(5) , 1477-86, (2005)

In the present communication different curcumin bioconjugates viz. 4,4'-di-O-glycinoyl-curcumin, 4,4'-di-O-d-alaninoyl-curcumin, 4,4'-di-O-(glycinoyl-di-N-piperoyl)-curcumin, 4,4'-di-O-piperoyl curcum...