Hippadine

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Names

[ CAS No. ]:
52886-06-3

[ Name ]:
Hippadine

[Synonym ]:
LYCORINE ALKALOID DERIV
Pratorine
4,5-Etheno-8,9-methylenedioxy-6-phenanthridone

Chemical & Physical Properties

[ Density]:
1.56g/cm3

[ Boiling Point ]:
422.1ºC at 760 mmHg

[ Molecular Formula ]:
C16H9NO3

[ Molecular Weight ]:
263.24800

[ Flash Point ]:
209.1ºC

[ Exact Mass ]:
263.05800

[ PSA ]:
39.94000

[ LogP ]:
2.77240

[ Index of Refraction ]:
1.785

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JI5025000
CHEMICAL NAME :
7H-(1,3)Dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridin- 7-one
CAS REGISTRY NUMBER :
52886-06-3
BEILSTEIN REFERENCE NO. :
0249337
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H9-N-O3
MOLECULAR WEIGHT :
263.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
45 mg/kg
SEX/DURATION :
male 3 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
REFERENCE :
PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.1- 1953- Volume(issue)/page/year: 49,252,1983

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-(5-fluoro-6-phenylpyrimidin-4-yl)-N-(propan-2-yl)piperazine-1-carboxamide
  • 6-{4-[3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1,4-diazepan-1-yl}pyridine-3-carbonitrile
  • 1-[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]-4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1,4-diazepane
  • 2-chloro-5-{pyrido[3,4-d]pyrimidin-4-yl}-4H,5H,6H,7H-thieno[3,2-c]pyridine
  • 5-Fluoro-4-phenyl-6-(4-propan-2-ylsulfonylpiperazin-1-yl)pyrimidine
  • 4,5-Dimethyl-6-{[1-(4-phenyloxane-4-carbonyl)piperidin-4-yl]methoxy}pyrimidine
  • N-[2-(5-chlorothiophen-2-yl)-2-methoxyethyl]-9-methyl-9H-purin-6-amine
  • 2-[1-(Cyclohexanesulfonyl)piperidin-4-yl]-6-phenyl-2,3-dihydropyridazin-3-one
  • 4-[(1-{2,5-Dimethylpyrazolo[1,5-a]pyrimidin-7-yl}piperidin-3-yl)methoxy]-2-methylpyridine
  • 6-[3-(4-methoxyphenyl)pyrrolidin-1-yl]-9-methyl-9H-purine
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