6-Hydroxy-2-naphthonitrile

Names

[ Name ]:
6-Hydroxy-2-naphthonitrile

[Synonym ]:
6-Hydroxy-2-naphthonitrile
MFCD01863480
6-hydroxynaphthalene-2-carbonitrile
6-Hydroxynaphthalen-2-carbonitril
2-Naphthalenecarbonitrile, 6-hydroxy-
6-Cyano-2-naphthol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
383.1±15.0 °C at 760 mmHg

[ Melting Point ]:
165.5-170.5 °C(lit.)

[ Molecular Formula ]:
C₁₁H₇NO

[ Molecular Weight ]:
169.179

[ Flash Point ]:
185.5±20.4 °C

[ Exact Mass ]:
169.052765

[ PSA ]:
44.02000

[ LogP ]:
2.15

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.692

[ Storage condition ]:
-20?C Freezer

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Naphthalenecarbonitrile,6-methoxy-
6-Bromo-2-naphthol
(3,4-dimethylphenyl) benzoate
Copper cyanide
2-Naphthol
2-Naphthalenol,6-bromo-, 2-acetate
6-acetoxy-[2]naphthonitrile
2-Bromo-6-methoxynaphthalene
(5R,6S)-5,6-dihydroxy-5,6-dihydronaphthalene-2-carbonitrile
benzoate of α,α,α',α'-tetrabromo-3,4-xylenol

DownStream

6-amidino-2-naphthol methanesulfonate
6-Cyano-2-Naphthyl Trifluoromethanesulfonate
6-Hydroxy-2-naphthoic acid
RARECHEM AL BW 0995
6-Methyl-2-naphthol
6-Ethoxynaphthalene-2-carbonitrile,
6-Amidino-2-naphthyl-4-aminomethylbenzoate dimethanesulfonate
6-amidino-2-naphthol
6-Cyano-2-naphthoic acid

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and structure-activity study of protease inhibitors. V. Chemical modification of 6-amidino-2-naphthyl 4-guanidinobenzoate.

Chem. Pharm. Bull. 41(1) , 117-25, (1993)

By developing 6-amidino-2-naphthyl 4-guanidinobenzoate (I, FUT-175) as a basic structure, its various derivatives were synthesized and their inhibitory activities on trypsin, plasmin, kallikrein, thro...

Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides.

Org. Biomol. Chem. 13(11) , 3351-62, (2015)

Proteoglycans (PGs) are macromolecules that consist of long linear polysaccharides, glycosaminoglycan (GAG) chains, covalently attached to a core protein by the carbohydrate xylose. The biosynthesis o...

Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors.

Bioorg. Med. Chem. 18(13) , 4601-5, (2010)

Nine newly 6-cyano-2-naphthyl substituted diarylpyrimidines (DAPY) were synthesized as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. The antiviral and cytotoxicity...

6-hydroxy-2,4-dioxo-N-phenyl-1H-pyrimidine-5-carboxamide
6-Hydroxy-2-naphthaleneacetic acid methyl ester
6-Hydroxy-2-methyl-1H-indole-3-carboxylic acid
6-Hydroxy-2-[3-[(2,4-dihydroxyphenyl)azo]phenyl]-7-[(2,5-dimethylphenyl)azo]-1H-naphth[1,2-d]imidazole-8-sulfonic acid sodium salt
6-hydroxy-2-(3-hydroxyphenyl)-2,3-dihydrochromen-4-one
6-Hydroxy-2-(propylsulfanyl)pyrimidin-4(3H)-on