Maytansine,3-de[2-(acetylmethylamino)-1- oxopropoxy]-4,5-deepoxy-2,3,4,5-tetradehydro- 22-demethyl-,(2E,4E)-

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Names

[ CAS No. ]:
52978-30-0

[ Name ]:
Maytansine,3-de[2-(acetylmethylamino)-1- oxopropoxy]-4,5-deepoxy-2,3,4,5-tetradehydro- 22-demethyl-,(2E,4E)-

[Synonym ]:
deepoxynormaysine
Maysine,5-deepoxy-4,5-didehydro-22-demethyl-,(E)
(3E,5E,7R,84S,10E,12E)-14-chloro-84-hydroxy-15,7r-dimethoxy-3,9c,11-trimethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5,10,12-tetraene-82,14-dione
(2E,4E)-4,5-deepoxy-22-demethyl-2,3,4,5-tetradehydro-3-deoxy-maytansinol

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
759.9ºC at 760 mmHg

[ Molecular Formula ]:
C27H33ClN2O6

[ Molecular Weight ]:
517.01400

[ Flash Point ]:
413.4ºC

[ Exact Mass ]:
516.20300

[ PSA ]:
106.12000

[ LogP ]:
5.15320

[ Index of Refraction ]:
1.599

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2E)-3-De(2-(acetylmethylamino)-1-oxopropoxy)-2,3-didehydro-22-demethylmaytansine

DownStream

Related Compounds

  • methyl 4-(3-Fluorophenylamino)benzoate
  • 6-Oxa-4-azaspiro[2.4]heptane-5,7-dione
  • Methyl 2-(4-piperidin-1-ylphenyl)-1,3-thiazole-4-carboxylate
  • 6-(2-Methoxyethoxy)pyridin-2-amine
  • {1-Oxaspiro[4.5]decan-2-yl}methanesulfonyl chloride
  • Ethyl 3-ortho-tolyl-1h-indole-2-carboxylate
  • Methyl 6-acetamido-[1,1'-biphenyl]-3-carboxylate
  • 1-(5-Bromo-2-fluorophenyl)propan-2-one
  • d0-DMDSSO crosslinker
  • N-(5-aminopyrimidin-2-yl)-3-chlorobenzamide
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