1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine

Names

[ CAS No. ]:
53-31-6

[ Name ]:
1-benzhydryl-4-(1,3-benzodioxol-5-ylmethyl)piperazine

[Synonym ]:
Medibazine [INN:DCF]
Medibazina [DCIT]
1-benzhydryl-4-benzo[1,3]dioxol-5-ylmethyl-piperazine
Benzhydryl-1-piperonyl piperazine
Medibazine
Piperazine,1-diphenylmethyl-4-piperonyl
EINECS 200-168-7
Medibazinum [INN-Latin]
Vialibran
1-(Diphenylmethyl)-4-piperonylpiperazine

Chemical & Physical Properties

[ Density]:
1.207g/cm3

[ Boiling Point ]:
503.2ºC at 760mmHg

[ Molecular Formula ]:
C25H26N2O2

[ Molecular Weight ]:
386.48600

[ Flash Point ]:
139.9ºC

[ Exact Mass ]:
386.19900

[ PSA ]:
24.94000

[ LogP ]:
4.19830

[ Index of Refraction ]:
1.633

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6650000
CHEMICAL NAME :
Piperazine, 1-diphenylmethyl-4-piperonyl-
CAS REGISTRY NUMBER :
53-31-6
BEILSTEIN REFERENCE NO. :
0901009
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C25-H26-N2-O2
MOLECULAR WEIGHT :
386.53
WISWESSER LINE NOTATION :
T56 BO DO CHJ C1- AT6N DNTJ DYR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
41 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 151,313,1964

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,3-benzodioxol-5-ylmethyl methanesulfonate
  • N-Benzhydrylpiperazine
  • Piperonyl alcohol

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-(3-Chloro-4-fluorophenyl)-5-methyl-1,2-oxazol-4-ol
  • 1-(2-cyclobutylethyl)-5-cyclopropyl-1H-1,2,3-triazole-4-carbothioamide
  • rac-tert-butyl N-{2-[(1R,3R)-3-amino-2,2-dimethylcyclopropyl]phenyl}carbamate
  • (1-{bicyclo[2.2.1]heptan-2-yl}-3-methyl-1H-pyrazol-4-yl)methanesulfonyl chloride
  • 2-[1-(6-Bromopyridin-2-yl)cyclopropyl]-2-hydroxyacetic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[2-(5-Methylfuran-2-yl)pyrimidin-4-yl]methanamine
  • Tert-butyl 4-[4-(pyrrolidin-3-yl)phenyl]-1,2,3,6-tetrahydropyridine-1-carboxylate
  • 1-Cyclobutyl-3-(5-methylfuran-2-yl)propane-1,3-dione
  • Perfluoropropane-1,2,3-tricarboxylic acid fluoride