N-Hydroxy-2-aminofluorene
Suppliers
Names
[ CAS No. ]:
53-94-1
[ Name ]:
N-Hydroxy-2-aminofluorene
[Synonym ]:
N-hydroxy-N-2-fluorenamine
N-Hydroxy-2-fluorenamine
2-NHOH-fluorene
N-Hydroxy-N-2-aminofluorene
7-Hydroxyaminofluorene
2-hydroxylaminofluorene
N-Fluorene-2-yl-hydroxylamine
2-Fluorenylhydroxylamine
N-2-Fluorenylhydroxylamine
N-Hydroxy-aminofluorene
Chemical & Physical Properties
[ Molecular Formula ]:
C13H11NO
[ Molecular Weight ]:
197.23300
[ Exact Mass ]:
197.08400
[ PSA ]:
32.26000
[ LogP ]:
3.13190
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NC3570000
- CHEMICAL NAME :
- Hydroxylamine, N-fluoren-2-yl-
- CAS REGISTRY NUMBER :
- 53-94-1
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 24
- MOLECULAR FORMULA :
- C13-H11-N-O
- MOLECULAR WEIGHT :
- 197.25
- WISWESSER LINE NOTATION :
- L B656 HHJ EMQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 mg/kg/9W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1600 mg/kg/17W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Mammal - dog Cells - not otherwise specified
- DOSE/DURATION :
- 100 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3974,1982 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970
Safety Information
[ HS Code ]:
2928000090
Synthetic Route
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%