[R-(R*,S*)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol hydrochloride
Suppliers
Names
[ CAS No. ]:
530-35-8
[ Name ]:
[R-(R*,S*)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol hydrochloride
[Synonym ]:
Nethamine hydrochloride
l-N-Ethylephedrine hydrochloride
Menetyl
2-Methylethylamino-1-phenyl-1-propanol hydrochloride
Novedrin hydrochloride
EINECS 208-476-3
l-1-Phenyl-2-methylethylaminopropan-1-ol hydrochloride
Chemical & Physical Properties
[ Density]:
0.995g/cm3
[ Boiling Point ]:
294.8ºC at 760mmHg
[ Molecular Formula ]:
C12H19NO
[ Molecular Weight ]:
193.28500
[ Exact Mass ]:
193.14700
[ PSA ]:
23.47000
[ LogP ]:
2.06020
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DO5775000
- CHEMICAL NAME :
- Benzyl alcohol, alpha-(1-(ethylmethylamino)ethyl)-, hydrochloride, (-)-
- CAS REGISTRY NUMBER :
- 530-35-8
- LAST UPDATED :
- 199312
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H19-N-O.Cl-H
- MOLECULAR WEIGHT :
- 229.78
- WISWESSER LINE NOTATION :
- QYR&Y1&N2&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 3,465,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 550 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,289,1942
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 39,382,1950
Safety Information
[ HS Code ]:
2922199090
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%