2-amino-5-(methylthio)-1,3,4-thiadiazole

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Names

[ CAS No. ]:
5319-77-7

[ Name ]:
2-amino-5-(methylthio)-1,3,4-thiadiazole

[Synonym ]:
2-Amino-5-methylthio-1,3,4-thiadiazole
MFCD00175752
2-Amino-5-methylthio-1,3,4-thidiazole
EINECS 203-573-7
2-amino-5-methyl-mercapto-1,3,4-thiadiazole
5-methylthio-1,3,4-thiadiazole-2-ylamine
2-AMINO-5-METHYLTHIO-134-THIADIAZOLE
5-(Methylthio)-1,3,4-thiadiazol-2-amine

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
318.1ºC at 760mmHg

[ Melting Point ]:
178-181 °C(lit.)

[ Molecular Formula ]:
C3H5N3S2

[ Molecular Weight ]:
147.22200

[ Flash Point ]:
146.2ºC

[ Exact Mass ]:
146.99200

[ PSA ]:
106.07000

[ LogP ]:
0.77230

[ Index of Refraction ]:
1.662

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI3540000
CHEMICAL NAME :
1,3,4-Thiadiazole, 2-amino-5-(methylthio)-
CAS REGISTRY NUMBER :
5319-77-7
BEILSTEIN REFERENCE NO. :
0118749
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H5-N3-S2
MOLECULAR WEIGHT :
147.23
WISWESSER LINE NOTATION :
T5NN DSJ CZ ES1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,484,1977

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Amino-1,3,4-thiadiazole-2-thiol
  • Methyl bromide
  • methyl iodide
  • Dimethyl sulfate
  • Chloromethane
  • (bis-methylsulfanyl-methylene)-thiosemicarbazide
  • methyl thiocyanate
  • Thiosemicarbazide
  • [(amino-methylsulfanyl-methylidene)amino]thiourea
  • (amino-methylsulfanyl-methylene)-dithiocarbazic acid methyl ester

DownStream

  • 2-methylsulfanylimidazo[2,1-b][1,3,4]thiadiazole
  • 2-BROMO-5-(METHYLTHIO)-1,3,4-THIADIAZOLE
  • N-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide
  • ethyl N-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)carbamate

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-AMINO-5-(3-METHYLBENZYLTHIO)-1,3,4-THIADIAZOLE
  • 2-Amino-5-Trifluoromethyl-1,3,4-Thiadiazole
  • 5-ethyl-1,3,4-thiadiazol-2-amine
  • 2-Amino-5-methyl-1,3,4-thiadiazole
  • 2-AMINO-5-PHENYL-1 3 4-THIADIAZOLE
  • 2-amino-5-cyclopropyl-1,3,4-thiadiazole