MEFLOQUINE
Suppliers
Names
[ CAS No. ]:
53230-10-7
[ Name ]:
MEFLOQUINE
[Synonym ]:
Pachycarpidine
OXYMATRINE
Kurainone
matrine,1-oxide
matrine n-oxide
Oxymatrine std.
Chemical & Physical Properties
[ Density]:
1.383g/cm3
[ Boiling Point ]:
415.7ºC at 760mmHg
[ Melting Point ]:
242-244ºC
[ Molecular Formula ]:
C17H16F6N2O
[ Molecular Weight ]:
378.31200
[ Flash Point ]:
205.2ºC
[ Exact Mass ]:
378.11700
[ PSA ]:
45.15000
[ LogP ]:
4.77670
[ Index of Refraction ]:
1.519
[ Storage condition ]:
Refrigerator, Under Inert Atmosphere
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VC0333400
- CHEMICAL NAME :
- 4-Quinolinemethanol, alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-, (R*,S*)-(+-)-
- CAS REGISTRY NUMBER :
- 53230-10-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H16-F6-N2-O
- MOLECULAR WEIGHT :
- 378.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 25 mg/kg/5W-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness Musculoskeletal - joints Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 123,894,1995