platinum sulfate

MOLECULAR FORMULA :

O8-Pt-S2

MOLECULAR WEIGHT :

387.21

WISWESSER LINE NOTATION :

.PT..S-O4*2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

281 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

397 mg/kg

SEX/DURATION :

female 8 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

397 mg/kg

SEX/DURATION :

lactating female 1 day(s) post-birth

TOXIC EFFECTS :

Reproductive - Effects on Newborn - behavioral

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Rodent - hamster Ovary

DOSE/DURATION :

50 umol/L

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 151,293,1985 *** REVIEWS *** ACGIH TLV-TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.002 mg(Pt)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,213,1971 OSHA PEL (Gen Indu):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.002 mg(Pt)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.002 mg(Pt)/m3 (dust) JAN 1993 OEL-AUSTRALIA:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-BELGIUM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-DENMARK:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-FINLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-GERMANY:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-HUNGARY:STEL 0.002 mg(Pt)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.002 mg(Pt)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV