Ethyl 1-piperidinecarboxylate

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Names

[ CAS No. ]:
5325-94-0

[ Name ]:
Ethyl 1-piperidinecarboxylate

[Synonym ]:
N-Carbethoxypiperidine
MFCD00047470
Ethyl 1-piperidinecarboxylate
Ethyl piperidine-1-carboxylate
1-Piperidinecarboxylic acid, ethyl ester

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
218.3±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H15NO2

[ Molecular Weight ]:
157.210

[ Flash Point ]:
85.9±18.7 °C

[ Exact Mass ]:
157.110275

[ PSA ]:
29.54000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.469

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM6300000
CHEMICAL NAME :
1-Piperidinecarboxylic acid, ethyl ester
CAS REGISTRY NUMBER :
5325-94-0
BEILSTEIN REFERENCE NO. :
0118408
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H15-N-O2
MOLECULAR WEIGHT :
157.24
WISWESSER LINE NOTATION :
T6NTJ AVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,321,1952

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperidine
  • Ethyl chloroformate
  • 1-Chloroethyl ethyl carbonate
  • (E)-1-(2-nonenyl)piperidine
  • Ethyl carbonate
  • isobutoxymethylpiperidine
  • Ethyl trifluoroacetate

DownStream

  • 5-Nonanone
  • DMBP
  • 1-Methylpiperidine
  • Piperidine
  • Pyridine
  • 3,5-Dibromopyridine
  • 4-Piperidinemethanol
  • bis(2-thienyl) ketone
  • monochloroethane
  • Carbonic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • tert-butyl 4-[2-(acetylsulfanyl)ethyl]-1-piperidinecarboxylate
  • 2-Methyl-2-propanyl 4-[1-(methylamino)ethyl]-1-piperidinecarboxylate
  • 2-Methyl-2-propanyl 4-[2-(4-piperidinyl)ethyl]-1-piperidinecarboxylate
  • 2-Methyl-2-propanyl 4-{(1S)-1-[(methylsulfonyl)oxy]ethyl}-1-piperidinecarboxylate
  • SA 57
  • tert-Butyl 3-amino-3-ethylpiperidine-1-carboxylate