Ethyl (2-amino-1,3-thiazol-4-yl)acetate

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Names

[ CAS No. ]:
53266-94-7

[ Name ]:
Ethyl (2-amino-1,3-thiazol-4-yl)acetate

[Synonym ]:
Ethyl 2-(2-aminothiazol-4-yl)acetate
MFCD00005330
Ethyl (2-amino-1,3-thiazol-4-yl)acetate
(2-Amino-4-thiazolyl)acetic Acid Ethyl Ester
Ethyl-2-(2-amino-4-thiazole-4-yl) acetate
EINECS 258-452-1
4-Thiazoleacetic acid, 2-amino-, ethyl ester
Ethyl (2-AMino-4-thiazolyl)acetate
Ethyl 2-Amino-4-Thiazoleacetate
ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate
Ethyl 2-aminothiazole-4-acetate

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
318.5±17.0 °C at 760 mmHg

[ Melting Point ]:
92-94 °C(lit.)

[ Molecular Formula ]:
C7H10N2O2S

[ Molecular Weight ]:
186.232

[ Flash Point ]:
146.4±20.9 °C

[ Exact Mass ]:
186.046295

[ PSA ]:
93.45000

[ LogP ]:
0.66

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.576

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-4-thiazoleacetic acid
  • Ethanol
  • Ethyl 2-bromo-3-oxobutanoate
  • Ethyl acetoacetate
  • Ethyl 4-bromo-3-oxobutanoate
  • Ethyl 2-Chloroacetoacetate

DownStream

  • Ethyl 2-chlorothiazole-4-acetate
  • 2-(2-Acetamidothiazol-4-yl)acetic acid
  • 2-Amino-4-thiazoleacetic acid
  • Ethyl (2-formamido-1,3-thiazol-4-yl)acetate
  • 1,3-Thiazol-4-ylacetic acid
  • ETHYL 2-(2-CHLOROACETAMIDO)-4-THIAZOLEACETATE
  • ethyl 2-(2-acetamido-1,3-thiazol-4-yl)acetate
  • 2-[[(4-AMINOPHENYL)SULFONYL]AMINO]-4-THIAZOLEACETIC ACID
  • 2-(2-Amino-1,3-thiazol-4-yl)acetamide
  • 4-Thiazoleacetic acid, ethyl ester

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Dichloridobis[ethyl 2-(2-amino-1,3-thia-zol-4-yl)acetate-κ(2)O,N(3)]cadmium.

Acta Crystallogr. Sect. E Struct. Rep. Online 68(6) , m788-m789, (2012)

The asymmetric unit of the title compound, [CdCl(2)(C(7)H(10)N(2)O(2)S)(2)], contains two complex molecules with similar configurations. The Cd(II) atoms are each six-coordinated by two thiazole N and...

Bis(2-amino-thia-zole-4-acetato)aquazinc(II).

Acta Crystallogr. Sect. E Struct. Rep. Online 65(12) , m1517-m1517, (2009)

In the title compound, [Zn(C(5)H(5)N(2)O(2)S)(2)(H(2)O)], the central Zn atom (2 site symmetry) is five-coordinated by two N and three O atoms [Zn-N = 2.047 (3) Å, Zn-O = 2.099 (2) and 1.974 (4) Å] in...

Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus

Bioorg. Med. Chem. 22(7) , 2280-93, (2014)

Novel heteroaryl-containing benzamide derivatives were synthesized and screened using an in vitro assay measuring increases in glucose uptake and glucokinase activity stimulated by 10mM glucose in rat...


More Articles

Related Compounds

  • Methyl (2-amino-1,3-thiazol-4-yl)acetate
  • methyl (2-amino-1,3-thiazol-4-yl)acetate hydrochloride
  • (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethyl (2-amino-1,3-thiazol-4-yl)acetate
  • ETHYL 2-(2-AMINO-1,3-THIAZOL-4-YL)ACETATE HYDROCHLORIDE
  • Ethyl {2-[(4-phenoxyphenyl)amino]-1,3-thiazol-4-yl}acetate
  • Ethyl (2-{[4-(4-chlorophenoxy)butanoyl]amino}-1,3-thiazol-4-yl)acetate
  • 5-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]-1-methyl-1H-pyrazole-4-carboxylic acid
  • rac-2-[(2R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-2-amido]benzoic acid
  • 3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethyl-N-(propan-2-yl)butanamido]propanoic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethyl-N-(2-methylpropyl)butanamido]acetic acid
  • 2-(1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-5-yl}-N-(2-methylpropyl)formamido)acetic acid
  • 3-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-4-yl]formamido}-2-methylbutanoic acid
  • 2-{1-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]azetidin-3-yl}acetic acid
  • (2S)-1-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]pyrrolidine-2-carboxylic acid
  • (2S,3R)-2-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-3-methoxybutanoic acid
  • rac-tert-butyl N-[(1R,2S)-2-hydroxy-3,3-dimethylcyclobutyl]carbamate
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