1,2-Propanediol,3-(2-methylphenoxy)-, 1-carbamate
Suppliers
Names
[ CAS No. ]:
533-06-2
[ Name ]:
1,2-Propanediol,3-(2-methylphenoxy)-, 1-carbamate
[Synonym ]:
2-hydroxy-3-(o-tolyloxy)propyl carbamate
2-Carbamoyloxy-3-o-tolyloxy-propan-1-ol
carbamic acid-(2-hydroxy-3-o-tolyloxy-propyl ester)
Mephenesin carbamate
1,2-Propanediol,3-(o-tolyloxy)-,1-carbamate
3-o-Toloxy-2-hydroxypropyl 1-carbamate
Tolseram
1-Hydrazinocarbonyloxy-3-(o-methylphenoxy)-2-propanol
Kimavoxyl
3-(o-Methylphenoxy)-1,2-propandiol-1-carbamat
Carbamidsaeure-(2-hydroxy-3-o-tolyloxy-propylester)
3-o-Tolyloxy-2-hydroxypropyl 1-carbamate
2-Hydroxy-3-o-tolyloxypropyl 1-carbamate
SQ 2303
Chemical & Physical Properties
[ Density]:
1.222g/cm3
[ Boiling Point ]:
461.4ºC at 760mmHg
[ Molecular Formula ]:
C11H15NO4
[ Molecular Weight ]:
225.24100
[ Flash Point ]:
232.8ºC
[ Exact Mass ]:
225.10000
[ PSA ]:
81.78000
[ LogP ]:
1.53030
[ Index of Refraction ]:
1.547
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FB2710000
- CHEMICAL NAME :
- Carbamic acid, 2-hydroxy-3-(o-tolyloxy)propyl ester
- CAS REGISTRY NUMBER :
- 533-06-2
- BEILSTEIN REFERENCE NO. :
- 1880597
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C11-H15-N-O4
- MOLECULAR WEIGHT :
- 225.27
- WISWESSER LINE NOTATION :
- ZVO1YQ1OR B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1050 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 413 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1050 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 490 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 982 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 385 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960
Safety Information
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%