5-bromo-6-methoxy-8-nitroquinoline

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Names

[ CAS No. ]:
5347-15-9

[ Name ]:
5-bromo-6-methoxy-8-nitroquinoline

[Synonym ]:
5-bromo-6-methoxy-8-nitro-quinoline
5-Brom-6-methoxy-8-nitro-chinolin
Quinoline,5-bromo-6-methoxy-8-nitro

Chemical & Physical Properties

[ Density]:
1.676g/cm3

[ Boiling Point ]:
411ºC at 760 mmHg

[ Molecular Formula ]:
C10H7BrN2O3

[ Molecular Weight ]:
283.07800

[ Flash Point ]:
202.4ºC

[ Exact Mass ]:
281.96400

[ PSA ]:
67.94000

[ LogP ]:
3.43730

[ Index of Refraction ]:
1.67

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VB0250000
CHEMICAL NAME :
Quinoline, 5-bromo-6-methoxy-8-nitro-
CAS REGISTRY NUMBER :
5347-15-9
BEILSTEIN REFERENCE NO. :
0207336
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H7-Br-N2-O3
MOLECULAR WEIGHT :
283.10
WISWESSER LINE NOTATION :
T66 BNJ GE HO1 JNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,62,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00917

Safety Information

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Methoxy-8-nitroquinoline
  • N-(3-bromo-4-methoxy-phenyl)acetamide
  • 4'-Methoxyacetanilide

DownStream

  • 5-bromo-6-methoxy-quinolin-8-amine
  • 5,6-dimethoxyquinolin-8-amine
  • 6-methoxy-5-(4-methoxyphenoxy)quinolin-8-amine
  • 6-methoxy-5-(4-methoxyphenoxy)-8-nitro-quinoline
  • 5,6-dimethoxy-8-nitro-quinoline

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-bromo-6-methoxy-8-nitroquinoline
  • 5-fluoro-6-methoxy-8-nitroquinoline
  • 5-bromo-6-methoxy-quinolin-8-amine
  • 5-bromo-6-fluoro-2-methyl-8-nitroquinoline
  • 5-Bromo-6-methoxy-4-methyl-pyridin-3-ylamine
  • 5-Bromo-6-methoxy-1H-indazole-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-Amino-2-methylcyclopentane-1-carbonitrile
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-(2-methoxy-5-methylphenyl)-2-{[4-oxo-3-(tetrahydrofuran-2-ylmethyl)-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine