4-phenyl-3-thiosemicarbazide

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Names

[ CAS No. ]:
5351-69-9

[ Name ]:
4-phenyl-3-thiosemicarbazide

[Synonym ]:
N-Phenylhydrazinecarbothioamide
EINECS 226-329-1
Hydrazinecarbothioamide, N-phenyl-
1-amino-3-phenylthiourea
hydrazinecarboximidothioic acid, N-phenyl-
MFCD00007615
N1-phenylhydrazine-1-carbothioamide
4-phenyl-3-thiosemicarbazide
N-phenylhydrazinecarbimidothioic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
287.4±23.0 °C at 760 mmHg

[ Melting Point ]:
138-140 °C(lit.)

[ Molecular Formula ]:
C7H9N3S

[ Molecular Weight ]:
167.232

[ Flash Point ]:
127.6±22.6 °C

[ Exact Mass ]:
167.051712

[ PSA ]:
82.17000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.727

[ Water Solubility ]:
methanol: 50 mg/mL, clear

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VT4025000
CHEMICAL NAME :
Semicarbazide, 4-phenyl-3-thio-
CAS REGISTRY NUMBER :
5351-69-9
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H9-N3-S
MOLECULAR WEIGHT :
167.25
WISWESSER LINE NOTATION :
ZMYUS&MR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,44,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,Xi

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
VT4025000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2930909090

Synthetic Route

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • 1-acetyl-4-phenyl-3-thiosemicarbazide
  • 4-methyl-4-phenyl-3-thiosemicarbazide
  • 2-Methyl-4-phenyl-3-thiosemicarbazide
  • 1-benzoyl-4-phenyl-3-thiosemicarbazide
  • 1-butyroyl-4-phenyl-3-thiosemicarbazide
  • 1-picolinoyl-4-phenyl-3-thiosemicarbazide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 6-bromo-2-methyl-3,4-dihydro-2H-1-benzopyran-3-carboxylic acid
  • 8-Cyclopropyl-1-(propan-2-yl)-1,8-diazaspiro[4.5]decan-4-amine
  • tert-Butyl-DL-alanine