5-(4-DIMETHYLAMINOBENZYLIDENE)RHODANINE

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Names

[ CAS No. ]:
536-17-4

[ Name ]:
5-(4-DIMETHYLAMINOBENZYLIDENE)RHODANINE

[Synonym ]:
4(5H)-thiazolone, 5-[[4-(dimethylamino)phenyl]methylene]-2-mercapto-, (5Z)-
4-Dimethylaminobenzylidenerhodanine
5-(4-Dimethylamino-benzylidene)-2-thioxo-thiazolidin-4-one
5-(4-Dimethylaminobenzylidene)-2-thioxo-4-thiazolidinone
5-(4-(Dimethylamino)benzylidene)-2-mercaptothiazol-4(5H)-one
5-[[4-(Dimethylamino)phenyl]methylene]-2-thioxo-4-thiazolidinone
4-Thiazolidinone, 5-[[4- (dimethylamino)phenyl]methylene]-2-thioxo-
5-(4-DIMETHYLAMINOBENZYLIDENE)RHODANINE
EINECS 208-625-2
(5Z)-5-[4-(Dimethylamino)benzylidene]-2-thioxo-1,3-thiazolidin-4-one
p-Dimethylaminobenzalrhodanine
4-Thiazolidinone, 5-[[4-(dimethylamino)phenyl]methylene]-2-thioxo-, (5Z)-
4-Dimethylaminobenzalrhodanine
MFCD00064857

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
430ºC at 760mmHg

[ Melting Point ]:
285-288 °C(lit.)

[ Molecular Formula ]:
C12H12N2OS2

[ Molecular Weight ]:
264.366

[ Flash Point ]:
213.8ºC

[ Exact Mass ]:
264.039093

[ PSA ]:
89.73000

[ LogP ]:
2.25

[ Index of Refraction ]:
1.703

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VI8090000
CHEMICAL NAME :
Rhodanine, 5-(p-(dimethylamino)benzylidene)-
CAS REGISTRY NUMBER :
536-17-4
BEILSTEIN REFERENCE NO. :
0189065
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H12-N2-O-S2
MOLECULAR WEIGHT :
264.38
WISWESSER LINE NOTATION :
T5SYMV EHJ BUS E1U1R DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,11,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD603-561 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6021 No. of Facilities: 139 (estimated) No. of Industries: 4 No. of Occupations: 4 No. of Employees: 768 (estimated) No. of Female Employees: 321 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VI8090000

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • Rhodanine
  • p-Dimethylaminobenzaldehyde
  • Benzenamine,N,N-dimethyl-4-[(phenylimino)methyl]-

DownStream

  • 5-[[4-(dimethylamino)phenyl]methylidene]-2-ethylsulfanyl-1,3-thiazol-4-one
  • (5E)-5-[[4-(dimethylamino)phenyl]methylidene]-3-[[4-(piperidine-1-carbonyl)anilino]methyl]-2-sulfanylidene-1,3-thiazolidin-4-one
  • 4-Thiazolidinone,5-[[4-(dimethylamino)phenyl]methylene]-3-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-2-thioxo-

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Histochemical study of the accumulation of copper in the liver of sheep.

Res. Vet. Sci. 42(1) , 73-81, (1987)

Six Merino sheep were dosed orally with a 0.2 per cent solution of copper sulphate, six others were undosed controls. Liver biopsies were obtained and stained for copper by the p-dimethylaminobenzylid...

Casassas E, et al.

Analyst 109(9) , 1159-1163, (1984)

Use of 5-(4-dimethylaminobenzylidene)rhodanine in quantitating silver grains eluted from autoradiograms of biological material.

Anal. Biochem. 154 , 104, (1986)

5-(4-Dimethylaminobenzylidene)rhodamine, a silver-specific dye, was used in a colorimetric assay to quantitate the autoradiographic deposition of silver onto X-ray film after exposure to sodium dodecy...


More Articles


Related Compounds

  • 5-(4-Iodobenzylidene)rhodanine
  • 5-(4-dimethylamino-benzylidene)-4-thioxo-thiazolidin-2-one
  • 5-[[4-(dimethylamino)phenyl]methylidene]-4-sulfanylidene-1,3-selenazolidin-2-one
  • 5-((4-Chlorophenyl)sulfonyl)-N-hydroxy-2-furancarboximidamide
  • 5-[[4-(dimethylamino)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
  • 5-[(4-dimethylaminophenyl)methylidene]imidazolidine-2,4-dione
  • 3-Fluoro-4-(thiophen-3-yl)benzaldehyde
  • 1-(3-Fluoro-4-(pyridin-3-yl)phenyl)-N-methylmethanamine
  • {[3-Fluoro-4-(thiophen-3-yl)phenyl]methyl}(propan-2-yl)amine
  • 7-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
  • 3-Methyl-4-(thiophen-3-yl)benzaldehyde
  • [3-Fluoro-4-(thiophen-3-yl)phenyl]methanamine
  • 1-[3-Fluoro-4-(thiophen-2-yl)phenyl]methanamine
  • (3-Fluoro-4-pyridin-2-ylphenyl)methanamine
  • 4'-Fluoro-2-methyl-[1,1'-biphenyl]-4-carbaldehyde
  • 3-Fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzenemethanamine
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