Indeno[1,2,3-gh]tetraphene

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Names

[ CAS No. ]:
5385-75-1

[ Name ]:
Indeno[1,2,3-gh]tetraphene

[Synonym ]:
Dibenzo<a,e>fluoranthene
Dibenz[a,e]aceanthrylene
2,3,5,6-Dibenzofluoranthene
Indeno[1,2,3-gh]tetraphene

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
552.3±17.0 °C at 760 mmHg

[ Melting Point ]:
232ºC

[ Molecular Formula ]:
C₂₄H₁₄

[ Molecular Weight ]:
302.368

[ Flash Point ]:
282.0±15.1 °C

[ Exact Mass ]:
302.109558

[ LogP ]:
7.63

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.913

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HM9799000

CHEMICAL NAME :: Dibenz(a,e)aceanthrylene

CAS REGISTRY NUMBER :: 5385-75-1

BEILSTEIN REFERENCE NO. :: 2120920

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C24-H14

MOLECULAR WEIGHT :: 302.38

WISWESSER LINE NOTATION :: L C65 K666 S6 1A A&J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2880 ug/kg/15W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Embryo

DOSE/DURATION :: 1 umol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,379,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,321,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,321,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
40

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2902909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Differences in metabolic activation of dibenzo[a,e]fluoranthene characterized by 32P-postlabeling in two mouse fibroblast models.

Cancer Lett. 61(3) , 207-13, (1992)

The formation of DNA adducts was investigated in mouse fibroblasts from two different tissues--embryos and adult lung--after incubation with dibenzo[a,e]fluoranthene (DBF) or its major proximate metab...

Dibenzo[a,e]fluoranthene.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 321-5, (1983)

Metabolic activation of dibenzo(a,e)fluoranthene, a nonalternant carcinogenic polycyclic hydrocarbon, in liver homogenates.

Cancer Res. 40(5) , 1742-9, (1980)

7-methylindeno[1,2,3-gh]tetraphene
1,2,3,4-tetrahydroindeno[1,2,3-gh]tetraphene
3,4-dihydroindeno[1,2,3-gh]tetraphene-3,4-diol
(1s,2s)-1,2-dihydroindeno[1,2,3-gh]tetraphene-1,2-diol
4b1,5,10,15-Tetraazanaphtho[1,2,3-gh]tetraphene-2,3,7,8,12,13-hexaol
Indeno[1,2,3-de]tetraphene
9-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(2-methoxyphenyl)-2-(trifluoromethyl)-9,10-dihydrochromeno[8,7-e][1,3]oxazin-4(8H)-one
2-ethyl-3-(4-fluorophenyl)-N,N,5-trimethylpyrazolo[1,5-a]pyrimidin-7-amine
ethyl 2-(2-methoxyethyl)-6-oxo-1H-pyrimidine-5-carboxylate
Methyl 2-(3,6-dichloropyridine-2-amido)benzoate
7-(2-chlorophenyl)-1,3-dimethyl-5-((2-oxo-2-(pyrrolidin-1-yl)ethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
3-(4-chlorophenyl)-9-(3-(2-oxopyrrolidin-1-yl)propyl)-9,10-dihydrochromeno[8,7-e][1,3]oxazin-4(8H)-one
C16H19FN2O2S2
N-{2-[(1H-indol-6-ylcarbonyl)amino]ethyl}-1H-indole-2-carboxamide
Ethyl 3-amino-3-(3-pyridyl)propionate hydrochloride
(2Z)-2-[(5-bromo-1-benzofuran-2-yl)methylidene]-6-hydroxy-4-methyl-7-[(4-methylpiperidin-1-yl)methyl]-1-benzofuran-3(2H)-one

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